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Table 2 Mutation frequency in non-HSV DNA.

From: Assessing the contribution of the herpes simplex virus DNA polymerase to spontaneous mutations

Virusa

Mutation Frequencyb (%)

HSV-2 SB5

1.7, 2.0, 1.7c

HSV-2 SB5PR

2.0, 1.8, 2.1

HSV-2 6652

0.7, 0.9, 1.1

HSV-2 6652PR

1.3, 1.0, 1.5

HSV-2 83D

0.8, 1.1, 1.0

HSV-2 83D PR

1.6, 1.2, 1.8

HSV-2 6757

4.1, 3.4, 4.9

HSV-2 6757PR

1.2, 1.1, 1.1

HSV-1 SC16

2.6, 2.2, 2.1

PAAr5

3.5, 3.6, 4.1

  1. aVirus labeled PR represents pol-recombinant virus. bMutation frequency = (number of white colonies for test sample/ number of blue colonies for test sample) - (number of white colonies in control sample/number of blue colonies in control sample) × 100. cThree independent experiments were performed, with data presented from experiment 1, 2 and 3, respectively.
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BMC Infectious Diseases

ISSN: 1471-2334

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