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Table 6 Treatment uptake in study cohorts receiving opioid substitution therapy

From: A systematic review of Hepatitis C virus treatment uptake among people who inject drugs in the European Region

Author, year

% treated (# treated/# of treatment candidates

SVR (%) (# with sustained viral response/# treated)

Cournot et al, 2004

31% of antibody+ (23/75)

Intent-to-treat: 36% (11/31)1

 

47% of RNA+ (23/49)

 
 

72% of other (23/32)

 

Cullen et al, 2007

3% of antibody+ (3/104)

NA

 

10% of RNA+ (3/29)

 

Schulte et al, 20102

9% of antibody+ (26/301)

Intent-to-treat: 69% (18/26)

As-treated: 86% (18/21)

Witteck et al, 20112

15% of RNA+ (29/193)

Intent-to-treat: 52% (13/25)

  1. Antibody+ = study participants who are hepatitis C antibody-positive
  2. RNA+ = study participants who are hepatitis C RNA-positive
  3. Other = study participants who are hepatitis C RNA-positive and meet additional treatment criteria
  4. 1. Calculated according to the number of treatment outcomes (N=31) rather than the number of patients who initiated therapy (N=23)
  5. 2. Study cohort received heroin maintenance therapy