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Table 5 Treatment uptake in study cohorts of people who inject drugs (current and former)

From: A systematic review of Hepatitis C virus treatment uptake among people who inject drugs in the European Region

Author, year

% treated (# treated/# of treatment candidates

SVR (%) (# with sustained viral response/# treated)

Broers et al, 2005

61% of RNA+ (11/18)

Intent-to-treat: 56% (6/11)

As-treated: 100% (3/3)

Cournot et al, 2004

39% of antibody+ (58/150)

Intent-to-treat: 22% (15/68)1

 

57% of RNA+ (58/102)

 
 

71% of other (58/82)

 

Crespo et al, 2001

64% of antibody+ (268/416)

NA

Gazdag et al, 2010

47% of RNA+ (39/83)

NA

Guadagnino et al, 2007

31% of RNA+ (53/169)

Intent-to-treat: 55% (29/53)

As-treated: 85% (29/34)

Hernandez et al, 2009

0% of RNA+ (0/4)

NA

Jowett et al, 2000

20% of antibody+ (50/253)

Intent-to-treat: 36% (18/50)

 

29% of RNA+ (50/172)

 
 

50% of other (50/100)

 

Kieran et al, 2011

21% of RNA+ (67/327)

Intent-to-treat: 43% (29/67)

Perez-Alvarez et al, 2012

56% of RNA+ (15/27)

NA

Reiberger et al, 2011

32% of RNA+ (201/637)

NA

van der Veen, 2009

48% of RNA+ (35/73)

NA

  1. Antibody+ = study participants who are hepatitis C antibody-positive
  2. RNA+ = study participants who are hepatitis C RNA-positive
  3. Other = study participants who are hepatitis C RNA-positive and meet additional treatment criteria
  4. 1. Calculated according to the number of treatment outcomes (N=68) rather than the number of patients who initiated therapy (N=58)