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Table 3 Treatment uptake as defined by percentage of hepatitis C RNA-positive study participants who received treatment

From: A systematic review of Hepatitis C virus treatment uptake among people who inject drugs in the European Region

Author, year % treated (# treated/# of treatment candidates) SVR (%) (# with sustained viral response/# treated)
Backmund et al, 2001 50% (50/100) Intent-to-treat: 36% (18/50)
Broers et al, 2005 61% (11/18) Intent-to-treat: 56% (6/11)
As-treated: 100% (3/3)
Cournot et al, 2004 54% (81/151) Intent-to-treat: 26% (26/99)1
Cullen et al, 2007 10% (3/29) NA
Ebner et al, 2009 23% (17/75) Intent-to-treat: 88% (15/17)
As-treated: 88% (15/17)
Gazdag et al, 2010 47% (39/83) NA
Grando-Lemaire et al, 2002 28% (27/97) Intent-to-treat: 19% (5/27)
As-treated: 33% (5/15)
Guadagnino et al, 2007 31% (53/169) Intent-to-treat: 55% (29/53)
As-treated: 85% (29/34)
Hernandez et al, 2009 0% (0/4) NA
Jack et al, 2009 25% (30/118) Intent-to-treat: 62% (13/21)
As-treated: 77% (13/17)
Jowett et al, 2000 29% (50/172) Intent-to-treat: 36% (18/50)
Kieran et al, 2011 21% (67/327) Intent-to-treat: 43% (29/67)
Lindenburg et al, 2011 30% (58/196) Intent-to-treat: 65% (37/57)
As-treated: 77% (37/48)
McCormick et al, 2008 46% (6/13) Intent-to-treat: 83% (5/6)
As-treated: 83% (5/6)
Moussalli et al, 20102 2% (2/113) NA
Moussalli et al, 20102 38% (85/224) Intent-to-treat: 43% (37/85)
Perez-Alvarez et al, 2012 56% (15/27) NA
Perut et al, 2009 9% (12/137) NA
Reiberger et al, 2011 32% (201/637) NA
van der Veen, 2009 48% (35/73) NA
Wilkinson et al, 2008 14% (63/441) As-treated: 51% (25/49)3
Witteck et al, 2011 15% (29/193) Intent-to-treat: 52% (13/25)
  1. 1. Calculated according to the number of treatment outcomes (N=99) rather than the number of patients who initiated therapy (N=81)
  2. 2. The study by Moussalli et al includes separate study populations for an observational phase (N=113) and an intervention phase (N=224), and those study populations are represented by two separate records in this table.
  3. 3. Calculated according to the number of treatment outcomes (N=49) rather than the number of patients who completed therapy (N=58)