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Table 3 Gene investigated for mutations responsible of resistance to different drugs and sensitivity percentage of resistant strains presenting mutation in the particular gene [85].

From: Clinical peculiarities of tuberculosis

Drug Gene arbouring mutations Sensitivity
Rifampicin rpoB > 98%
Isoniazid katG, inhA 80-90%
Quinolones girA 70-90%
Amikacin, Capreomycin, Kanamycin Rrs 50-90%
Ethambutol embB 70-80%