Table 3 Gene investigated for mutations responsible of resistance to different drugs and sensitivity percentage of resistant strains presenting mutation in the particular gene [85].
Drug | Gene arbouring mutations | Sensitivity |
|---|---|---|
Rifampicin | rpoB | > 98% |
Isoniazid | katG, inhA | 80-90% |
Quinolones | girA | 70-90% |
Amikacin, Capreomycin, Kanamycin | Rrs | 50-90% |
Ethambutol | embB | 70-80% |