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Table 3 Effects of Isoniazid prophylaxis on all cause mortality

From: Efficacy of isoniazid prophylactic therapy in prevention of tuberculosis in children: a meta–analysis

Study HIV status of participants Participant ages Risk ratio(95% CI) p value
Madhi et al. (2011) [19] Positive <4 months(median 96 days, range 91–120 days) 1.00(0.68,1.48) 0.986
Madhi et al. (2011) [19] Negative <4 months(median 96 days, range 91–120 days) 0.90(0.49,1.65) 0.733
Zar et al. (2007) [18] Positive <51 months (median 24.7 months, IQR 9.4–51.6 months) 0.46(0.22,0.95) 0.015
Egsmose [20] Negative 0–15 years 0.94(0.33,2.66) 0.91
All four studies combined    0.86(0.63,1.17) 0.168
Excluding studies that INH was initiated at age 4 months    0.58(0.31, 1.09) 0.092