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Table 2 Comorbidities, clinical features, and treatment outcomes of EPTB and PTB in Brazil, 2007- 2011

From: Epidemiology of extrapulmonary tuberculosis in Brazil: a hierarchical model

Characteristics N* Categories EPTB (%) (n = 53,853) PTB (%) (n = 356,341) P value**
HIV/AIDS Negative 24,072 (69.2) 149,526 (83.8) <0.001
(213,336) Positive 10,755 (30.8) 28,983 (16.2)  
Alcoholism No 46,056(91.6) 249,995 (82.0) <0.001
(355,292) Yes 4,236 (8.4) 55,005 (18.0)  
Diabetes No 48,121 (96.1) 279,415 (92.9) <0.001
(350,756) Yes 1,960 (3.9) 21,260 (7.1)  
Mental illness No 49,114 (98.1) 293,039 (97.3) <0.001
(351,236) Yes 960 (1.9) 8,123 (2.7)  
Other diseases No 38,142 (83.8) 229,706 (84.7) 0.001
(316,784) Yes 7,357 (16.2) 41,579 (15.3)  
Admission type New cases 50,126 (87.6) 290,431 (81.5) <0.001
(413,559) Relapse 2,178 (3.8) 23,013 (6.5)  
  Readmission after dropout 1,386(2.4) 23,191 (6.5)  
  Unknown 151 (0.3) 1,026 (0.3)  
  Transfer 3,376 (5.9) 18,681 (5.2)  
TST Negative 4,745 (29.3) 14,461 (28.0) <0.001
(67,942) Positive 11,481 (70.7.2) 37,255 (72.0)  
AFB smear Negative 23,936 (80.0) 82,602 (26.5) <0.001
(341,807) Positive 5,997 (20.0) 229,272 (73.5)  
Culture Negative 6,775 (59.3) 22,103 (33.2) <0.001
(78,004) Positive 4,648 (40.7) 44,478 (66.8)  
Histopathology Negative 884 (3.8) 2,184 (9.9) <0.001
(44,855) Positive 21,903(96.2) 19.884 (90.1)  
DOT Not performed 28,727 (64.7) 153.811 (51.7) <0.001
(341,831) Performed 15,696 (35.3) 143,597 (48.3)  
Outcome status Cure 30,186(71.5) 186,428 (70.1) <0.001
(308,112) Dropout 3,429 (8.1) 33,016 (12.4)  
  Death by TB 1,564 (3.7) 10,718 (4.0)  
  Death by other causes 3,024 (7.2) 11,046 (4.2)  
  Transfer 3,967 (9.4) 23,566 (8.9)  
  MDR-TB 28 (0.1) 1,140 (0.4)  
  1. *Number of valid observations. **Pearson’s chi-squared test.
  2. HIV/AIDS: human immunodeficiency virus/acquired immunodeficiency syndrome. TST: tuberculin skin test. AFB: acid-fast bacilli. DOT: Directly Observed Therapy. EPTB: Extrapulmonary tuberculosis. PTB: pulmonary tuberculosis.