Table 1 Annual incidence of patients with each type of invasive pneumococcal disease (IPD), sinusitis, and otitis media at National Taiwan University Hospital from 2000 to 2012
From: Decline in the incidence of invasive pneumococcal disease at a medical center in Taiwan, 2000–2012
Disease | Incidence expressed as no. of patients per 10,000 admission (no. of patients) | Pvalue | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2000 (n = 55920) | 2001 (n = 66743) | 2002 (n = 62177) | 2003 (n = 54574) | 2004 (n = 64186) | 2005 (n = 67853) | 2006 (n = 70814) | 2007 (n = 73534) | 2008 (n = 74505) | 2009 (n = 78756) | 2010 (n = 79710) | 2011 (n = 81594) | 2012 (n = 85253) | ||
IPD | 9.8 | 7.6 | 8.0 | 5.9 | 8.4 | 4.6 | 4.0 | 3.0 | 4.6 | 3.6 | 3.8 | 3.1 | 2.1 | <0.001 |
All bacteremia | 9.3 | 7.3 | 7.1 | 5.1 | 7.9 | 4.1 | 3.8 | 2.9 | 4.2 | 3.4 | 3.4 | 2.7 | 1.9 | <0.001 |
Primary bacteremia | 6.8 | 4.8 | 4.2 | 3.7 | 5.9 | 3.8 | 2.8 | 2.2 | 3.4 | 3.0 | 2.5 | 2.0 | 0.8 | <0.001 |
Bacteremic pneumonia | 0.9 | 1.9 | 1.6 | 0.9 | 1.1 | 0.3 | 0.7 | 0.5 | 0.4 | 0.4 | 0.6 | 0.4 | 0.6 | <0.001 |
Empyema | 1.3 | 0.4 | 1.3 | 1.1 | 0.3 | 0.3 | 0.3 | 0.3 | 0.7 | 0.1 | 0.4 | 0.6 | 0.7 | 0.070 |
Peritonitis | 0.4 | 0.1 | 0.2 | 0.0 | 0.2 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | < 0.009 |
Meningitis | 0.5 | 0.3 | 0.8 | 0.2 | 0.9 | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | 0.3 | 0.1 | 0.0 | <0.001 |
Non-IPD | ||||||||||||||
Pneumonia without bacteremia | 16.8 | 18.4 | 24.1 | 19.1 | 23.2 | 23.4 | 27.1 | 23.0 | 25.6 | 22.1 | 23.5 | 15.0 | 12.7 | <0.054 |
Sinusitis | 0.2 | 0.3 | 0.3 | 0.2 | 0.6 | 0.3 | 0.3 | 0.4 | 0.4 | 0.0 | 0.3 | 0.1 | 0.2 | 0.439 |
Otitis media | 0.4 | 0.3 | 0.2 | 0.2 | 0.5 | 0.3 | 0.3 | 0.4 | 0.3 | 0.3 | 0.0 | 0.2 | 0.4 | 0.69 |