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Table 6 Univariate and multivariate hazard ratios for the association between male circumcision and clearance of transient genital HPV infection

From: Male circumcision and the incidence and clearance of genital human papillomavirus (HPV) infection in men: the HPV Infection in men (HIM) cohort study

 

Any HPV

Oncogenic HPV

Non-Oncogenic HPV

   

Univariatea

Multivariateb

  

Univariatea

Multivariatec

  

Univariatea

Multivariated

Circumcision

Inf./ Total

%

HR (95% CI)

AHR (95% CI)

Inf./ Total

%

HR (95% CI)

AHR (95% CI)

Inf./ Total

%

HR (95% CI)

AHR (95% CI)

No

2806/ 4434

63.3

1.00

1.00

1106/ 1624

68.1

1.00

1.00

1700/ 2810

60.5

1.00

1.00

Yes

1665/ 2515

66.2

0.95 (0.88 – 1.03)

0.98 (0.90 – 1.06)

745/ 1066

69.9

0.88 (0.77 – 1.00)

0.91 (0.80 – 1.04)

920/ 1449

63.5

0.99 (0.89 – 1.10)

1.01 (0.91 – 1.13)

Total

4471/ 6949

   

1851/ 2690

   

2620/ 4259

   
  1. aAdjusted for age and country;
  2. bCox model stratified by country and age, and adjusted for lifetime number of female sexual partners, recent number of male anal sex partners, smoking status, HPV status at baseline, and six-month visit compliance status;
  3. cCox model stratified by country and age, and adjusted for lifetime number of female sexual partners, lifetime number of male anal sex partners, HPV status at baseline, and six-month visit compliance status;
  4. dCox model stratified by country and age, and adjusted for recent number of female sexual partners, recent number of male anal sex partners, smoking status, HPV status at baseline, and six-month visit compliance status.
  5. NOTE: Unit of analysis: infections; Excluded 120 infections that were a combination of persistent and transient infection; Abbreviations: Inf., infections; HR, hazard ratio; CI, confidence interval; AHR, adjusted hazard ratio.