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Table 5 Univariate and multivariate hazard ratios for the association between male circumcision and clearance of genital HPV infection

From: Male circumcision and the incidence and clearance of genital human papillomavirus (HPV) infection in men: the HPV Infection in men (HIM) cohort study

  Any HPV Oncogenic HPV Non-Oncogenic HPV
    Univariatea Multivariateb    Univariatea Multivariatec    Univariatea Multivariated
Circumcision Inf./ Total % HR (95% CI) AHR (95% CI) Inf./ Total % HR (95% CI) AHR (95% CI) Inf./ Total % HR (95% CI) AHR (95% CI)
No 4353/ 5981 72.8 1.00 1.00 1748/ 2266 77.1 1.00 1.00 2605/ 3715 70.1 1.00 1.00
Yes 2548/ 3398 75.0 0.92 (0.86 – 0.99) 0.95 (0.88 – 1.02) 1089/ 1410 77.2 0.86 (0.78 – 0.96) 0.90 (0.81 – 1.00) 1459/ 1988 73.4 0.97 (0.89 – 1.05) 0.98 (0.89 – 1.07)
Total 6901/ 9379     2837/ 3676     4064/ 5703    
  1. aAdjusted for age and country;
  2. bCox model stratified by country and age, and adjusted for lifetime number of female sexual partners, recent number of male anal sex partners, smoking status, HPV status at baseline, and six-month visit compliance status;
  3. cCox model stratified by country and age, and adjusted for lifetime number of female sexual partners, lifetime number of male anal sex partners, HPV status at baseline, and six-month visit compliance status;
  4. dCox model stratified by country and age, and adjusted for recent number of female sexual partners, recent number of male anal sex partners, smoking status, HPV status at baseline, and six-month visit compliance status.
  5. NOTE: Unit of analysis: infections; Abbreviations: Inf., infections; HR, hazard ratio; CI, confidence interval; AHR, adjusted hazard ratio.