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Table 3 Univariate and multivariate hazard ratios for the association between male circumcision and incidence of genital HPV infection

From: Male circumcision and the incidence and clearance of genital human papillomavirus (HPV) infection in men: the HPV Infection in men (HIM) cohort study

 

Any HPV

Oncogenic HPV

Non-Oncogenic HPV

   

Univariatea

Multivariateb

  

Univariatea

Multivariatec

  

Univariatea

Multivariated

Circumcision

Inf./ Total

%

HR (95% CI)

AHR (95% CI)

Inf./ Total

%

HR (95% CI)

AHR (95% CI)

Inf./ Total

%

HR (95% CI)

AHR (95% CI)

No

555/ 1174

47.3

1.00

1.00

584/ 1795

32.5

1.00

1.00

596/ 1441

41.4

1.00

1.00

Yes

359/ 745

48.2

1.08 (0.92 – 1.27)

1.08 (0.91 – 1.27)

369/ 1035

35.7

1.11 (0.94 – 1.31)

1.11 (0.94 – 1.31)

372/ 917

40.6

1.09 (0.93 – 1.28)

1.11 (0.94 – 1.30)

Total

914/ 1919

   

953/ 2830

   

968/ 2358

   
  1. aAdjusted for age and country;
  2. bAdjusted for country, age, marital status, lifetime number of female sexual partners, recent number of female sexual partners, recent number of male anal sex partners, and six-month visit compliance status;
  3. cAdjusted for country, age, marital status, lifetime number of female sexual partners, recent number of female sexual partners, and recent number of male anal sex partners;
  4. dCox model stratified by age and adjusted for country, marital status, lifetime number of female sexual partners, recent number of female sexual partners, lifetime number of male anal sex partners, and six-month visit compliance status;
  5. NOTE: Unit of analysis: men; Inf., infections; HR, hazard ratio; CI, confidence interval; AHR, adjusted hazard ratio.