Longitudinal evaluation of candidate pro-inflammatory/anti-inflammatory cytokine and cytokine/receptor ratios categorized by incident neuropathic symptom status. Incident neuropathic symptoms developed within 12 weeks of starting cART. The control group refers to the symptom-free nested control group paired for previously identified risk factors. *refers to within-group differences from baseline, p < 0.05. # refers to between-group differences from baseline levels, p < 0.05. Horizontal bars indicate median values with interquartile ranges. Baseline refers to pre-cART levels. Abbreviations: IL, interleukin; sIL, soluble interleukin; TNFα, tumour necrosis factor-α.