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Table 1 Comparison of antimicrobial susceptibilities between 2004 and 2012

From: In vitro susceptibility of Escherichia colistrains isolated from urine samples obtained in mainland China to fosfomycin trometamol and other antibiotics: a 9-year surveillance study (2004–2012)

Antibiotica 10/2004–9/2005 (n = 168) 1/2007–12/2007 (n = 271) 7/2009–6/2010 (n = 262) 7/2011–6/2012 (n = 207) p
  S (%) MIC90(mg/L) S (%) MIC90(mg/L) S (%) MIC90(mg/L) S (%) MIC90(mg/L)  
FOS 99.4 2 95.9 1 95.0 4 93.2* 8 0.030
TZP 94.0 16 97.8 8 92.7 16 94.7 8 0.058
CXM 42.3 512 32.8 512 27.5* 512 30.9 512 0.015
CTX 53.0 128 37.6* 256 30.9* 512 36.2* 512 < 0.001
FEP 88.1 16 76.4* 32 61.5*,** 64 75.4*,*** 32 < 0.001
IMP 100 0.25 99.6 0.25 99.6 0.125 99.5 0.125 1.000
AMK 94.6 4 95.6 4 92.7 8 93.2 4 0.519
NIT 78.6 64 83.0 64 91.6*,** 32 88.9* 64 < 0.001
LVX 31.0 32 28.0 32 28.2 32 32.4 32 0.693
  1. aDrug abbreviations: FOS, fosfomycin trometamol; TZP, piperacillin-tazobactam; CXM, cefuroxime; CTX, cefotaxime; FEP, cefepime; IMP, imipenem; AMK, amikacin; NIT, nitrofurantoin; LVX, levofloxacin.
  2. *compared to 10/2004–9/2005, p < 0.0083.
  3. **compared to 1/2007–12/2007, p < 0.0083.
  4. ***compared to 7/2009–6/2010, p < 0.0083.