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Table 2 Resolved results for sensitivity, specificity, PPV and NPV of FT MTB (culture and clinical diagnosis)

From: Evaluation of Fluorotype MTB for detection of Mycobacterium tuberculosis complex DNA in clinical specimens from a low-incidence country

 

No. of specimens with indicated results by culture and clinical data (n= 971)a

    
 

TB (n= 59)

no TB (n= 912)

    
 

FT MTB pos

FT MTB neg

FT MTB pos

FT MTB neg

Sensitivity

Specificity

PPV

NPV

Smear microscopy

(%)

(%)

(%)

(%)

(95% CI)

(95% CI)

(95% CI)

(95% CI)

Smear positive

43

0

0

3

100

100

100

100

 

(82.7)

(0)

(0)

(0.3)

(89.7-100)

(30.9-100)

(89.7-100)

(30.9-100)

Smear negative

9

7

10

899

56.3

98.9

47.3

99.2

 

(17.3)

(100)

(100)

(99.7)

(30.5-79.2)

(97.9-99.4)

(25.2-70.5)

(98.3-99.6)

All

52

7

10

902

88.1

98.9

83.8

99.2

(76.4-94.6)

(97.9-99.4)

(72.8-91.5)

(98.3-99.6)

  1. aTB, tuberculosis; pos, positive; neg, negative; PPV, positive predictive value; NPV, negative predictive value.