Anti-IL-10 antibody could partially neutralize the inhibitory effect of rhIFN-α
2a on IL-17 production by PBMCs from CAHB patients (n = 61). PBMCs from CAHB patients were cultured with or without rhIFN-α 2a, anti-IL-10 antibody in combination with anti-CD3 and anti-CD28 antibodies for 72 h. Concentrations of IL-17 in the supernatants were detected by ELISA. Anti-IL-10 antibody (10 mg/ml) could partially neutralize inhibitory role of rhIFN-α 2a on IL-17 production. Columns represent mean values (mean + SEM).