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Table 4 Semiquantitative comparative analysis of the various mycobacterial antigens in the individual cases of pulmonary and lymph node tuberculous detected by immunohistochemistry done on formalin fixed paraffin embedded tissues

From: Differential in vivo expression of mycobacterial antigens in Mycobacterium tuberculosisinfected lungs and lymph node tissues

 

Secreted antigens

Somatic antigens

 

MPT32

MPT44

MPT46

MPT51

MPT53

MPT59

MPT63

MPT64

Mce1A

Hsp65

MPT57

Lung 1

+++++

-

+++++

+++++

+++++

++++

+++++

+++++

+++

+++++

++++

Lung 2

+++++

-

+++++

+++++

+++++

++++

+++++

+++++

+++

++

++

Lung 3

+++

+++

+++++

++++

++++

++++

++++

++++

++

++

+++

LN 1

-

-

-

-

-

SNC

-

+

+

+++

+++

LN 2

-

SNC

-

-

-

-

-

+

+++

+++, SNC

+++

LN 3

-

-

-

-

-

-

-

+

++

++++

++++

LN 4

-

-

-

-

-

-

-

+

+

++++

+

LN 5

-

-

-

-

-

-

-

+

+++, SNC

+++++

+++++

LN 6

+

-

-

-

-

SNC

-

++

++

++++

++++

LN 7

-

-

-

-

-

SNC

-

++

++

+++

+

LN 8

-

ND

-

-

SNC

SNC

-

++

+

+++

+++

LN 9

-

ND

-

-

-

-

-

++

++

+++

+++

LN 10

-

+

-

-

-

-

-

++

+

+++

++++

LN 11

-

ND

-

-

-

+

-

++

+

+++

+

LN 12

-

-

-

-

SNC

-

+

++

+++

+++

+++

LN 13

+

-

-

-

-

+

-

+++

+

+++++

+

LN 14

-

-

-

-

-

-

-

+++

+

+++

+++

LN 15

-

+

-

-

SNC

-

-

+++

+++

++++

++++

LN 16

+

SNC

-

-

-

-

+

+++

++

++

ND

LN 17

-

-

-

-

-

-

-

++

+

++

++++

  1. LN: Lymph node, SNC; staining in the necrotic centres, ND; not determined.
  2. +++++ ~ 80% positive granuloma cells, ++++ ~ 50% positive granuloma cells, +++ 10-25% positive granuloma cells, ++ 2-9% positive granuloma cells, + < 2% positive granuloma cells, - no staining.