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Table 3 Immunohistochemical analysis of in vivo expression of various mycobacterial antigens in the formalin fixed tissues obtained from Mycobacterium tuberculosis -infected lungs and lymph nodes, and non-tuberculous controls

From: Differential in vivo expression of mycobacterial antigens in Mycobacterium tuberculosisinfected lungs and lymph node tissues

  No. with positive results/total number (%)***
  Multibacillary lung tissues** Tuberculous lymphadenitis Non-TB controls
ZN staining 3/3 (100) 0/17 (0) 0/12 (0)
PCR* 3/3 (100) 17/17 (100) 0/12 (0)
Secreted antigens    
MPT32 3/3 (100) 3/17 (18) 0/12 (0)
MPT44 1/3 (33) 4/14 (28) 6/12 (50)
MPT46 3/3 (100) 0/17 (0) 1/12 (8)
MPT51 3/3 (100) 0/17 (0) 0/12 (0)
MPT53 3/3 (100) 3/17 (18) 1/12 (8)
MPT59 3/3 (100) 6/17 (35) 3/12 (25)
MPT63 3/3 (100) 2/17 (12) 2/12 (17)
MPT64 3/3 (100) 17/17 (100) 2/12 (17)
Somatic antigens    
Mce1A 3/3 (100) 17/17 (100) 8/12 (67)
Hsp65 3/3 (100) 17/17 (100) 12/12 (100)
MPT57 3/3 (100) 16/16 (100) 12/12 (100)
  1. *PCR, N-PCR for amplification of IS6110.
  2. **Vast number of bacilli were detectable by ZN staining.
  3. ***A case/control was labelled as positive if any positive signal was recorded in a lesion irrespective of the quality of stain.