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Table 2 Features of cases in the second season, divided in four groups

From: Bordetella pertussis: an underreported pathogen in pediatric respiratory infections, a prospective cohort study

 

Clinical suspicion

Clinical suspicion

Non-suspicion

Non-suspicion

RT-PCR positive

RT-PCR negative

RT-PCR positive

RT -PCR negative

N = 7

N = 42

N = 7

N = 250

(Figure 1, group C)

(Figure 1, group D)

(Figure 1, group E)

(Figure 1, group F)

Male, n

4

30

1

147

Age, months, mean (range)

14,8 (1,2-49,6)

4,8 (0,1-21,7)

3,8 (0,6 - 8,7)

7,6 (0,1-89,4)

Clinical features

    

In-hospital cases, n

6 (85,7%)

30 (71,4%)

5 (71,4%)

182 (72,8%)

Fever, n

3 (42,9%)

18 (42,9%)

1 (14,2%)

131 (52,4%)

Coughing, n

7 (100%)

41 (97,6%)

7 (100%)

207 (82,8%)

Rhinorrhea, n

7 (100%)

39 (92,9%)

7 (100%)

231 (92,4%)

Paroxysmal cough, n

6 (85,7%)

25 (59,5)

1 (14,2%)

27 (10,8%)

CRP > 40 mg/L, n

0 (0%)

3 (7,1%)

1 (14,2%)

26 (10,4%)

Oxygen therapy necessary, n

2 (28,6%)

15 (35,7%)

2 (28,6%)

105 (42,0 %)

Nasogastric feeding, n

1 (14,3%)

5 (11,9%)

0 (0,0%)

27 (10,8%)

Wheezing, n

3 (42,9%)

15 (35,7%)

1 (14,2%)

113 (45,2%)

Apnoe, n

0 (0%)

3 (7,1%)

0 (0,0%)

10 (4,0%)

Days of illness, mean (range)

18,3 (5–37)

9,7 (2–42)

10,4 (5–18)

8,3 (1–35)

Disease severity score, mean (range)

9,9 (0–19)

11,7 (0–24)

9,6 (3–18)

13,4 (0–27)

Disease severity score

    

<6

2

9

2

65

7-13

3

16

3

55

14-19

2

14

2

75

>20

0

3

0

55

Clinical diagnosis

    

Exclusively URTI

0

23

4

133

Exclusively LRTI

0

0

0

1

Combined URTI/LRTI

7

18

3

106

No URTI or LRTI

0

1

0

10

Pertussis diagnosis

    

PCR throat swab material, n

4

x

0

x

PCR NWS, n

3

x

7

x

Serology, positive, n

1

x

0

x

Culture, positive n

0

x

0

x

Viral (co)infection

    

None

1

7

2

37

1 virus

6

21

3

146

≥ 2 virusses

0

14

2

67

Antibiotic therapy

    

None

0

26

4

158

Amoxicillin, n

1

9

2

94

Claritromycine, n

7

7

1

8