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Table 4 Characteristics of the patients with pulmonary Mycobacterium avium complex disease with or without treatment success

From: The influence of environmental exposure on the response to antimicrobial treatment in pulmonary Mycobacterial avium complex disease

Variable Patients with treatment success Patients with treatment failure P value
  (n = 37) (n = 35)  
Age, years 60.3 ± 11.4 63.3 ± 8.8 0.34
Gender, female (%) 28 (75.7) 26 (74.3) 0.89
Underlying disease    
 Lung disease 7 (18.9) 12 (34.3) 0.14
 COPD 1 (2.7) 3 (8.6) 0.35
 Asthma 2 (5.4) 2 (5.7) >0.99
 Previous tuberculosis 2 (5.4) 3 (8.6) 0.67
 Previous malignant disease 8 (21.6) 4 (11.4) 0.25
 Diabetes mellitus 3 (8.1) 3 (8.6) >0.99
 Collagen vascular disease 3 (8.1) 6 (17.1) 0.30
Use of immunosuppressive agents 1 (2.7) 4 (11.4) 0.19
Use of inhaled corticosteroid 1 (2.7) 1 (2.9) >0.99
Smoking status (ex or current) 8 (21.6) 6 (17.1) 0.63
Alcohol drinking habit 8 (21.6) 9 (25.7) 0.78
Environmental exposure    
 Low soil exposure before treatment 31 (83.8) 20 (57.1) 0.01
 Low soil exposure after the start of treatment 35 (94.6) 15 (42.9) 0.0002
 Low soil exposure during observation 31 (83.8) 16 (45.7) 0.0007
 Bathing (≥1 per day) 35 (94.6) 33 (94.3) >0.99
 Shower use in a bathroom 29 (78.4) 26 (74.3) 0.68
 Swimming in a pool 2 (5.4) 0 (0.0) 0.49
Laboratory findings    
Negative smear 27 (73.0) 17 (48.6) 0.03
M. avium 26 (70.3) 30 (85.7) 0.23
M. intracellulare 10 (27.0) 5 (14.3)  
M. avium + M. intracellulare 1 (2.7) 0 (0.0)  
Radiographic findings    
 Any size of cavity 18 (48.6) 17 (48.6) >0.99
 Large cavity (≥2 cm) 6 (16.2) 9 (25.7) 0.32
 Bronchiectasis 34 (91.9) 31 (88.6) 0.71
Total length of follow-up time, months 53.8 ± 20.8 53.8 ± 19.5 0.90
  1. COPD, chronic obstructive pulmonary disease. The data show either the numbers (%) of patients or the means ± standard deviations. Low soil exposure is defined as no or less than 2 hours per week of soil-related activities.