Skip to main content

Table 4 Characteristics of the patients with pulmonary Mycobacterium avium complex disease with or without treatment success

From: The influence of environmental exposure on the response to antimicrobial treatment in pulmonary Mycobacterial avium complex disease

Variable

Patients with treatment success

Patients with treatment failure

P value

 

(n = 37)

(n = 35)

 

Age, years

60.3 ± 11.4

63.3 ± 8.8

0.34

Gender, female (%)

28 (75.7)

26 (74.3)

0.89

Underlying disease

   

 Lung disease

7 (18.9)

12 (34.3)

0.14

 COPD

1 (2.7)

3 (8.6)

0.35

 Asthma

2 (5.4)

2 (5.7)

>0.99

 Previous tuberculosis

2 (5.4)

3 (8.6)

0.67

 Previous malignant disease

8 (21.6)

4 (11.4)

0.25

 Diabetes mellitus

3 (8.1)

3 (8.6)

>0.99

 Collagen vascular disease

3 (8.1)

6 (17.1)

0.30

Use of immunosuppressive agents

1 (2.7)

4 (11.4)

0.19

Use of inhaled corticosteroid

1 (2.7)

1 (2.9)

>0.99

Smoking status (ex or current)

8 (21.6)

6 (17.1)

0.63

Alcohol drinking habit

8 (21.6)

9 (25.7)

0.78

Environmental exposure

   

 Low soil exposure before treatment

31 (83.8)

20 (57.1)

0.01

 Low soil exposure after the start of treatment

35 (94.6)

15 (42.9)

0.0002

 Low soil exposure during observation

31 (83.8)

16 (45.7)

0.0007

 Bathing (≥1 per day)

35 (94.6)

33 (94.3)

>0.99

 Shower use in a bathroom

29 (78.4)

26 (74.3)

0.68

 Swimming in a pool

2 (5.4)

0 (0.0)

0.49

Laboratory findings

   

Negative smear

27 (73.0)

17 (48.6)

0.03

M. avium

26 (70.3)

30 (85.7)

0.23

M. intracellulare

10 (27.0)

5 (14.3)

 

M. avium + M. intracellulare

1 (2.7)

0 (0.0)

 

Radiographic findings

   

 Any size of cavity

18 (48.6)

17 (48.6)

>0.99

 Large cavity (≥2 cm)

6 (16.2)

9 (25.7)

0.32

 Bronchiectasis

34 (91.9)

31 (88.6)

0.71

Total length of follow-up time, months

53.8 ± 20.8

53.8 ± 19.5

0.90

  1. COPD, chronic obstructive pulmonary disease. The data show either the numbers (%) of patients or the means ± standard deviations. Low soil exposure is defined as no or less than 2 hours per week of soil-related activities.