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Table 3 Characteristics of patients with pulmonary Mycobacterium avium complex disease with or without a relapse

From: The influence of environmental exposure on the response to antimicrobial treatment in pulmonary Mycobacterial avium complex disease

Variable

Patients without relapse

Patients with relapse

P value

 

(n = 37)

(n = 15)

 

Age, years

60.3 ± 11.4

64.6 ± 5.3

0.27

Gender, female (%)

28 (75.7)

10 (66.7)

0.51

Underlying disease

   

 Lung disease

7 (18.9)

5 (33.3)

0.29

 COPD

1 (2.7)

2 (13.3)

0.19

 Asthma

2 (5.4)

1 (6.7)

>0.99

 Previous tuberculosis

2 (5.4)

0 (0.0)

>0.99

 Previous malignant disease

8 (21.6)

3 (20.0)

>0.99

 Diabetes mellitus

3 (8.1)

2 (13.3)

0.62

 Collagen vascular disease

3 (8.1)

3 (20.0)

0.34

Immunosuppressive agents

1 (2.7)

1 (6.7)

0.50

Inhaled corticosteroid

1 (2.7)

1 (6.7)

0.50

Smoking status (ex or current)

8 (21.6)

3 (20.0)

>0.99

Alcohol drinking habit

8 (21.6)

6 (40.0)

0.19

Environmental exposure

   

 Low soil exposure before treatment

31 (83.8)

8 (53.3)

0.03

 Low soil exposure after the start of treatment

35 (94.6)

7 (46.7)

0.0003

 Low soil exposure during observation

31 (83.8)

6 (40.0)

0.005

 Bathing (≥1 per day)

35 (94.6)

15 (100)

>0.99

 Shower use in a bathroom

29 (78.4)

12 (80.0)

0.90

 Swimming in a pool

2 (5.4)

0 (0.0)

>0.99

Laboratory findings

   

 Negative smear

27 (73.0)

10 (66.7)

0.74

M. avium

26 (70.3)

13 (86.7)

0.44

M. intracellulare

10 (27.0)

2 (13.3)

 

M. avium + M. intracellulare

1 (2.7)

0 (0.0)

 

Radiographic findings

   

 Any size of cavity

18 (48.7)

4 (26.7)

0.15

 Large cavity (≥2 cm)

6 (16.2)

1 (6.7)

0.66

 Bronchiectasis

34 (91.9)

12 (80.0)

0.34

Total length of follow-up time, months

53.8 ± 20.8

60.0 ± 22.1

0.28

  1. COPD, chronic obstructive pulmonary disease. The data show either the numbers (%) of patients or the means ± standard deviations. Low soil exposure is defined as no exposure or less than 2 hours per week of soil-related activities.