Skip to main content

Table 3 Characteristics of patients with pulmonary Mycobacterium avium complex disease with or without a relapse

From: The influence of environmental exposure on the response to antimicrobial treatment in pulmonary Mycobacterial avium complex disease

Variable Patients without relapse Patients with relapse P value
  (n = 37) (n = 15)  
Age, years 60.3 ± 11.4 64.6 ± 5.3 0.27
Gender, female (%) 28 (75.7) 10 (66.7) 0.51
Underlying disease    
 Lung disease 7 (18.9) 5 (33.3) 0.29
 COPD 1 (2.7) 2 (13.3) 0.19
 Asthma 2 (5.4) 1 (6.7) >0.99
 Previous tuberculosis 2 (5.4) 0 (0.0) >0.99
 Previous malignant disease 8 (21.6) 3 (20.0) >0.99
 Diabetes mellitus 3 (8.1) 2 (13.3) 0.62
 Collagen vascular disease 3 (8.1) 3 (20.0) 0.34
Immunosuppressive agents 1 (2.7) 1 (6.7) 0.50
Inhaled corticosteroid 1 (2.7) 1 (6.7) 0.50
Smoking status (ex or current) 8 (21.6) 3 (20.0) >0.99
Alcohol drinking habit 8 (21.6) 6 (40.0) 0.19
Environmental exposure    
 Low soil exposure before treatment 31 (83.8) 8 (53.3) 0.03
 Low soil exposure after the start of treatment 35 (94.6) 7 (46.7) 0.0003
 Low soil exposure during observation 31 (83.8) 6 (40.0) 0.005
 Bathing (≥1 per day) 35 (94.6) 15 (100) >0.99
 Shower use in a bathroom 29 (78.4) 12 (80.0) 0.90
 Swimming in a pool 2 (5.4) 0 (0.0) >0.99
Laboratory findings    
 Negative smear 27 (73.0) 10 (66.7) 0.74
M. avium 26 (70.3) 13 (86.7) 0.44
M. intracellulare 10 (27.0) 2 (13.3)  
M. avium + M. intracellulare 1 (2.7) 0 (0.0)  
Radiographic findings    
 Any size of cavity 18 (48.7) 4 (26.7) 0.15
 Large cavity (≥2 cm) 6 (16.2) 1 (6.7) 0.66
 Bronchiectasis 34 (91.9) 12 (80.0) 0.34
Total length of follow-up time, months 53.8 ± 20.8 60.0 ± 22.1 0.28
  1. COPD, chronic obstructive pulmonary disease. The data show either the numbers (%) of patients or the means ± standard deviations. Low soil exposure is defined as no exposure or less than 2 hours per week of soil-related activities.