TY - JOUR AU - Hurst, Rebecca JM AU - Hopwood, Thomas AU - Gallagher, Amanda L. AU - Partridge, Frederick A. AU - Burgis, Timothy AU - Sattelle, David B. AU - Else, Kathryn J. PY - 2014 DA - 2014/09/27 TI - An antagonist of the retinoid X receptor reduces the viability of Trichuris muris in vitro JO - BMC Infectious Diseases SP - 520 VL - 14 IS - 1 AB - Trichuriasis is a parasitic disease caused by the human whipworm, Trichuris trichiura. It affects millions worldwide, particularly in the tropics. This nematode parasite burrows into the colonic epithelium resulting in inflammation and morbidity, especially in children. Current treatment relies mainly on general anthelmintics such as mebendazole but resistance to these drugs is increasingly problematic. Therefore, new treatments are urgently required. SN - 1471-2334 UR - https://doi.org/10.1186/1471-2334-14-520 DO - 10.1186/1471-2334-14-520 ID - Hurst2014 ER -