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Table 2 Comparison of biochemical and haematological measurements before and after antiretroviral treatment

From: Evaluating the utility of early laboratory monitoring of antiretroviral-induced haematological and hepatic toxicity in HIV-infected persons in Cameroon

Laboratory measurements Pre-ART Mean (SD) 15thDay Post-ART Mean (SD) Mean Difference (Pre-ART minus Post-ART) 95% CI of mean difference p-value from paired t-test
ALAT (U/L) 17.87 (20.48) 19.25 (12.01) −1.37 (23.10) −5.73-2.99 0.53
ASAT (U/L) 17.32 (11.87) 21.02 (14.12) −3.70 (16.61) −6.84- -0.56 0.02
Haemoglobin (g/dl) 10.86 (2.63) 10.36 (1.92) 0.50 (2.29) 0.08-0.92 0.02
Mean cell volume (fl) 79.62 (7.93) 83.49 (9.13) −3.86 (8.98) −5.95- -1.78 0.0004
Absolute leucocyte count (10 3 /μl) 6.21 (3.44) 4.84 (1.76) 1.37 (3.62) 0.66-2.09 0.0002
Absolute platelet count (10 5 /μl) 2.72 (1.07) 2.69 (1.14) 0.03 (1.18) −0.20- 0.25 0.82
  1. ART = antiretroviral therapy, ALAT = alanine aminotransferase, ASAT = aspartate aminotransferase, CI = confidence interval.