Characteristics and outcomes | CVC retained for more than 7 days since bacteremia (n = 16) | Removed within 7 days of bacteremia (n = 16) | Exchanged with antibiotic-coated catheters within 7 days of bacteremia (n = 8) | p-value | Ā |
---|---|---|---|---|---|
Ā | N (%) | N (%) | N (%) | Ā | Ā |
Median age (years), (range) | 52 (12ā74) | 62 (4ā83) | 55 (29ā67) | 0.24 | Ā |
Gender, male | 10 (62.5%) | 8 (50.0%) | 2 (25.0%) | 0.28 | Ā |
Type of cancer | Ā | Ā | Ā | > .99 | Ā |
āāHematologic malignancy | 6 (37.5%) | 6 (37.5%) | 3 (37.5%) | Ā | Ā |
āāSolid tumor | 10 (62.5%) | 10 (62.5%) | 5 (62.5%) | Ā | Ā |
Body temperature | Ā | Ā | Ā | 0.41 | Ā |
āāā¤ 36Ā°C | 2 (12.5%) | 0 (0%) | 1 (12.5%) | Ā | Ā |
āā36Ā°C ā38Ā°C | 6 (37.5%) | 5 (31.3%) | 1 (12.5%) | Ā | Ā |
āāā„ 38Ā°C | 8 (50.0%) | 11 (68.7%) | 6 (75.0%) | Ā | Ā |
MIC of vancomycin | Ā | Ā | Ā | 0.77 | Ā |
āā< 2.0 | 9 (56.2%) | 9 (56.2%) | 3 (37.5%) | Ā | Ā |
āāā„ 2.0 | 7 (43.8%) | 7 (43.8%) | 5 (62.5%) | Ā | Ā |
Number of lumens of catheters | Ā | Ā | Ā | 0.59 | Ā |
āāSingle | 7 (43.8%) | 6 (37.5%) | 1 (12.5%) | Ā | Ā |
āāDouble | 8 (50.0%) | 9 (56.3%) | 6 (75.0%) | Ā | Ā |
āāTriple | 1 (6.3%) | 1 (6.3%) | 1 (12.5%) | Ā | Ā |
CVC location | Ā | Ā | Ā | 0.22 | Ā |
āāSubclavian | 7 (43.8%) | 6 (37.5%) | 6 (75.0%) | Ā | Ā |
āāJugular | 2 (12.5%) | 0 | 0 | Ā | Ā |
āāBasilic | 7 (43.8%) | 10 (62.5%) | 2 (25.0%) | Ā | Ā |
Defervescence within 3 days of starting antibiotics | 11 (68.8%) | 14 (87.5%) | 6 (75.0%) | 0.49 | Ā |
Relapse within 3 months | 2 (12.5%) | 0 (0%) | 1 (12.5%) | 0.4 | Ā |
Death within 3 months | 8 (50.0%) | 4 (25.0%) | 0 (0%) | 0.034 | CVC retained vs CVC exchange: p = 0.02 |
Infection-related death within 3 months | 5 (31.3%) | 1 (6.3%) | 0 (0%) | 0.1 | Ā |