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Table 1 Clinical characteristics and outcomes

From: The use of minocycline-rifampin coated central venous catheters for exchange of catheters in the setting of staphylococcus aureus central line associated bloodstream infections

Characteristics and outcomes

CVC retained for more than 7 days since bacteremia (n = 16)

Removed within 7 days of bacteremia (n = 16)

Exchanged with antibiotic-coated catheters within 7 days of bacteremia (n = 8)

p-value

Ā 
Ā 

N (%)

N (%)

N (%)

Ā Ā 

Median age (years), (range)

52 (12ā€“74)

62 (4ā€“83)

55 (29ā€“67)

0.24

Ā 

Gender, male

10 (62.5%)

8 (50.0%)

2 (25.0%)

0.28

Ā 

Type of cancer

Ā Ā Ā 

> .99

Ā 

ā€ƒā€‰Hematologic malignancy

6 (37.5%)

6 (37.5%)

3 (37.5%)

Ā Ā 

ā€ƒā€‰Solid tumor

10 (62.5%)

10 (62.5%)

5 (62.5%)

Ā Ā 

Body temperature

Ā Ā Ā 

0.41

Ā 

ā€ƒā€‰ā‰¤ 36Ā°C

2 (12.5%)

0 (0%)

1 (12.5%)

Ā Ā 

ā€ƒā€‰36Ā°C āˆ’38Ā°C

6 (37.5%)

5 (31.3%)

1 (12.5%)

Ā Ā 

ā€ƒā€‰ā‰„ 38Ā°C

8 (50.0%)

11 (68.7%)

6 (75.0%)

Ā Ā 

MIC of vancomycin

Ā Ā Ā 

0.77

Ā 

ā€ƒā€‰< 2.0

9 (56.2%)

9 (56.2%)

3 (37.5%)

Ā Ā 

ā€ƒā€‰ā‰„ 2.0

7 (43.8%)

7 (43.8%)

5 (62.5%)

Ā Ā 

Number of lumens of catheters

Ā Ā Ā 

0.59

Ā 

ā€ƒā€‰Single

7 (43.8%)

6 (37.5%)

1 (12.5%)

Ā Ā 

ā€ƒā€‰Double

8 (50.0%)

9 (56.3%)

6 (75.0%)

Ā Ā 

ā€ƒā€‰Triple

1 (6.3%)

1 (6.3%)

1 (12.5%)

Ā Ā 

CVC location

Ā Ā Ā 

0.22

Ā 

ā€ƒā€‰Subclavian

7 (43.8%)

6 (37.5%)

6 (75.0%)

Ā Ā 

ā€ƒā€‰Jugular

2 (12.5%)

0

0

Ā Ā 

ā€ƒā€‰Basilic

7 (43.8%)

10 (62.5%)

2 (25.0%)

Ā Ā 

Defervescence within 3 days of starting antibiotics

11 (68.8%)

14 (87.5%)

6 (75.0%)

0.49

Ā 

Relapse within 3 months

2 (12.5%)

0 (0%)

1 (12.5%)

0.4

Ā 

Death within 3 months

8 (50.0%)

4 (25.0%)

0 (0%)

0.034

CVC retained vs CVC exchange: p = 0.02

Infection-related death within 3 months

5 (31.3%)

1 (6.3%)

0 (0%)

0.1

Ā