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Table 3 Cytokine levels in unstimulated PBMCs of HIV-infected subgroups

From: Proliferative capacity and cytokine production by cells of HIV-infected and uninfected adults with different helminth infection phenotypes in South Africa

Cytokine (pg/ml)

Phenotype subgroups

 

Median (minimum-maximum)

 

Egg+IgEhi(n = 10)

Egg+IgElo(n = 10)

Egg-IgEhi(n = 10)

Eggs-IgElo(n = 9)

Pro-inflammatory

IL-6

10762 (9.2–12044)

9158 (4066–12985)

10253 (192–12547)

12671 (1267–>10000)

IL-8

8666 (605–10845)

8653 (5927–11872)

10723 (6785–11994)

11934 (7936–13130)

TNFα

153 (0.46–469)

200 (19–1012)

68 (23–2759)

81(16–398)

Anti-inflammatory

    

IL-1RA

5369 (50–>10000)

6058 (2359–>10000)

>10000 (426–>10000)

>10000 (283–>10000)

Type one (Th1)

    

IL-2

0 (0–0)

1.4 (0–6.8)

0 (0–5.8)

1.09 (0–5.9)

IFNγ

0 (0–1.1)

2.0 (0–252)

1.2 (0.12–808)

0.4 (0–3.5)

IP-10

41 (4–118)

174 (12–7739)

48 (5–1051)

113 (0–640)

GM-CSF

105 (0–177)

85 (15–476)

47 (18–1997)

54 (8–292)

Type two (Th2)

    

IL-4

20 (3–21)

10 (3–23)

20 (10–48)

16 (13–18)

IL-5

0.1 (0–0.1)

0.08 (0–2.7)

0.2 (0.1–232)

(0.1–0.2)

IL-13

0 (0–11)

0.16 (0–161)

3.71 (0–2943)

0 (0–0)

Regulatory

    

IL-10

31 (0–280)

116 (29–406)

40 (4–403)

147 (3–801)

  1. Egg–Faecal helminth eggs, IgE–Ascaris lumbricoides-specific IgE, IgE hi/lo–high/low IgE in serum, IL-interleukin, IL–1RA interleukin-1 receptor antagonist; IFNγ–interferon gamma; IP-10–interferon-inducible protein 10, TNFα–Tumour necrosis factor alpha, GM-CSF–granulocyte-monocyte stimulation factor, RPMIc–omplete RPMI medium.