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Table 6 Factors associated with the presence of leucopenia

From: Prevalence and correlates of cytopenias in HIV-infected adults initiating highly active antiretroviral therapy in Uganda

Results of uni- and multivariable log-binomial regression models

Covariate

Univariable (n = 400)

Multivariable‡ (n = 397*)

 

PR (95% CI)

p value

PR (95% CI)

p value

CD4 count cells/μl

    

  <50

1

 

1

 

  50 to <200

0.23 (0.13 to 0.42)

<0.001

0.23 (0.13 to 0.42)

<0.001

  200 to <350

0.17 (0.08 to 0.37)

<0.001

0.17 (0.08 to 0.37)

<0.001

  ≥ 350

0.30 (0.07 to 1.22)

0.094

0.30 (0.07 to 1.22)

0.094

Sex

    

  Male

1

   

  Female

1.05 (0.64 to 1.74)

0.834

  

Age, years

    

  18 to < 30

1

   

  30 to < 35

1.16 (0.59 to 2.30)

0.669

  

  35 to < 41

1.07 (0.57 to 2.01)

0.822

  

  ≥ 41

0.97 (0.50 to 1.86)

0.918

  

BMI*

    

  under weight

1

   

  normal

2.15 (0.72 to 6.37)

0.168

  

  over weight

2.34 (0.75 to 7.29)

0.144

  

  Incomplete information*

-

-

  

HAART status at recruitment

   

  Not using HAART

1

   

  AZT-based HAART

0.20 (0.03 to 1.58)

0.128

  

  Non-AZT based HAART

0.89 (0.56 to 1.41)

0.616

  

Education level

    

  None

1

   

  Minimum Primary

0.39 (0.12 to 1.29)

0.124

  

  Minimum Secondary

0.48 (0.14 to 1.61)

0.234

  

  Tertiary

0.53 (0.14 to 2.03)

0.355

  

  Don’t know

-

-

  

Employment status

    

  Unemployed

1

   

  Employed

1.33 (0.66 to 2.69)

0.430

  

Marital status

    

  Not married

1

   

  Married

1.37 (0.85 to 2.20)

0.195

  

Presence/history of oral candidiasis

   

  No

1

   

  Yes

1.24 (0.74 to 2.10)

0.417

  

Presence/history of fever

    

  No

1

   

  Yes

0.77 (0.49 to 1.22)

0.272

  
  1. Multivariable model only includes variables for which data are shown below because all others were lacking significance.
  2. *Three participants with missing BMI could not be included in the log-binomial regression model because the outcome did not vary in this group.
  3. One participant with unknown education level was excluded from analysis because the outcome did not vary in this stratum.