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Table 5 Factors associated with the presence of thrombocytopenia

From: Prevalence and correlates of cytopenias in HIV-infected adults initiating highly active antiretroviral therapy in Uganda

Results of uni- and multivariable log-binomial regression models

Covariate

Univariable (n = 400)

Multivariable‡ (n = 397*)

 

PR (95% CI)

p value

PR (95% CI)

p value

Sex

    

  Male

1

 

1

 

  Female

0.33 (0.16 to 0.69)

0.003

0.32 (0.15 to 0.68)

0.003

HAART status at recruitment§

   

  Not on HAART

1

 

1

 

  On HAART

0.35 (0.16 to 0.76)

0.009

0.32 (0.14 to 0.75)

0.008

CD4 count cells/μl

    

  <50

1

   

  50 to < 200

0.40 (0.17 to 0.95)

0.037

  

  ≥ 200**

0.48 (0.18 to 1.33)

0.159

  

BMI

    

  under weight

1

   

  normal

0.90 (0.25 to 3.20)

0.873

  

  over weight

0.67 (0.16 to 2.75)

0.575

  

  Incomplete information*

-

-

  

Age, years

    

  18 to < 30

1

   

  30 to < 35

2.36 (0.76 to 7.34)

0.139

  

  35 to < 41

1.74 (0.57 to 5.27)

0.328

  

  ≥ 41

1.74 (0.56 to 5.40)

0.335

  

Education level

    

  None

1

   

  Minimum Primary

1.05 (0.13 to 8.63)

0.961

  

  Minimum Secondary

1.02 (0.12 to 8.62)

0.983

  

  Tertiary

0.58 (0.05 to 7.00)

0.667

  

  Don’t know

-

-

  

Employment status

    

  Unemployed

1

   

  Employed

2.62 (0.61 to 11.3)

0.196

  

Marital status

    

  Not married

1

   

  Married

1.50 (0.73 to 3.09)

0.274

  

Presence/history of oral candidiasis

   

  No

1

   

  Yes

1.44 (0.66 to 3.15)

0.358

  

Presence/history of fever

    

  No

1

   

  Yes

1.01 (0.50 to 2.06)

0.975

  
  1. Multivariable model only includes variables for which data are shown below because all others were lacking significance.
  2. §All participants on HAART were categorized into one group for this analysis because none of the 15 patients on AZT had thrombocytopenia.
  3. AZT = azidothymidine or zidovudine.
  4. *Three participants with missing BMI could not be included in the log-binomial regression model because the outcome did not vary in this group.
  5. **CD4 categories 200 to <350 and ≥ 350 were combined for this analysis because none of the participants with CD4 count ≥ 350 had thrombocytopenia.