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Table 5 Factors associated with the presence of thrombocytopenia

From: Prevalence and correlates of cytopenias in HIV-infected adults initiating highly active antiretroviral therapy in Uganda

Results of uni- and multivariable log-binomial regression models
Covariate Univariable (n = 400) Multivariable‡ (n = 397*)
  PR (95% CI) p value PR (95% CI) p value
Sex     
  Male 1   1  
  Female 0.33 (0.16 to 0.69) 0.003 0.32 (0.15 to 0.68) 0.003
HAART status at recruitment§    
  Not on HAART 1   1  
  On HAART 0.35 (0.16 to 0.76) 0.009 0.32 (0.14 to 0.75) 0.008
CD4 count cells/μl     
  <50 1    
  50 to < 200 0.40 (0.17 to 0.95) 0.037   
  ≥ 200** 0.48 (0.18 to 1.33) 0.159   
BMI     
  under weight 1    
  normal 0.90 (0.25 to 3.20) 0.873   
  over weight 0.67 (0.16 to 2.75) 0.575   
  Incomplete information* - -   
Age, years     
  18 to < 30 1    
  30 to < 35 2.36 (0.76 to 7.34) 0.139   
  35 to < 41 1.74 (0.57 to 5.27) 0.328   
  ≥ 41 1.74 (0.56 to 5.40) 0.335   
Education level     
  None 1    
  Minimum Primary 1.05 (0.13 to 8.63) 0.961   
  Minimum Secondary 1.02 (0.12 to 8.62) 0.983   
  Tertiary 0.58 (0.05 to 7.00) 0.667   
  Don’t know - -   
Employment status     
  Unemployed 1    
  Employed 2.62 (0.61 to 11.3) 0.196   
Marital status     
  Not married 1    
  Married 1.50 (0.73 to 3.09) 0.274   
Presence/history of oral candidiasis    
  No 1    
  Yes 1.44 (0.66 to 3.15) 0.358   
Presence/history of fever     
  No 1    
  Yes 1.01 (0.50 to 2.06) 0.975   
  1. Multivariable model only includes variables for which data are shown below because all others were lacking significance.
  2. §All participants on HAART were categorized into one group for this analysis because none of the 15 patients on AZT had thrombocytopenia.
  3. AZT = azidothymidine or zidovudine.
  4. *Three participants with missing BMI could not be included in the log-binomial regression model because the outcome did not vary in this group.
  5. **CD4 categories 200 to <350 and ≥ 350 were combined for this analysis because none of the participants with CD4 count ≥ 350 had thrombocytopenia.