Table 4 Arguments pro and against a short duration of antibiotic therapy
Arguments for a short treatment | Arguments for a longer treatment |
|---|---|
No comorbid conditions | Immune depression |
Source control | No source control |
Low MICs, high bactericidal titers | MDR , XDR bacterias |
Initial appropriate therapy | Low bactericidal titers |
Easy PK and tissue diffusion | Poor PK and tissue diffusion |
Source control appropriate | Foreign materials |
No foreign material | Slow, partial clinical response |
Rapid clinical improvement | Â |