Protective efficacy of Toxoplasma gondiicalcium-dependent protein kinase 1 (TgCDPK1) adjuvated with recombinant IL-15 and IL-21 against experimental toxoplasmosis in mice

Table 2 Mean cyst burden per mouse brain 4 weeks after challenge with 20 cysts of Toxoplamsa gondii strain PRU per mouse

*The reduction of brain cysts were from the values for the blank control group.
**The same superscript letter means no statistically significant difference (P > 0.05) between different experimental groups, whereas different superscript letters mean statistically significant difference among different experimental groups from the same measurement (P < 0.05).
^A The superscript letter A means no statistically significant difference (P > 0.05) between the groups of pVAX I, PBS and control.
^B The superscript letter B means no statistically significant difference (P > 0.05) between the groups of pVAX-CDPK1 and pVAX-IL-21-IL-15, but it means significant differences of the No. of brain cysts in these two groups in contrast to the control group.
^C The superscript letter C means significant differences of the No. of brain cysts in the group of pVAX-IL-21-IL-15 + pVAX-CDPK1 in contrast to the groups of pVAX-CDPK1 and pVAX-IL-21-IL-15 (P < 0.05).

ISSN: 1471-2334