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Table 2 Symptoms and signs other than diarrhea in 30 volunteers experimentally infected with ETEC strain TW10598

From: Experimental infection of healthy volunteers with enterotoxigenic Escherichia coliwild-type strain TW10598 in a hospital ward

Target dose (CFU) 1 × 106 1 × 107 1 × 108 1 × 109
No. of volunteers 3 8 7 12
Nausea 1 (33%) 5 (63%) 5 (71%) 7 (58%)
Abdominal pain 0 4 (50%) 7 (100%) 7 (58%)
Abdominal cramping 0 1 (13%) 7 (100%) 6 (50%)
Excessive flatus 1 (33%) 1 (13%) 5 (71%) 5 (42%)
Decreased appetite 0 2 (25%) 5 (71%) 5 (42%)
Bloating 1 (33%) 0 0 6 (50%)
Vomiting 0 1 (13%) 0 2 (17%)
Constipation 0 0 0 1 (8%)
Headache 2 (67%) 2 (25%) 4 (57%) 5 (42%)
Malaise 0 2 (25%) 4 (57%) 5 (42%)
Fever 0 4 (50%) 1 (14%) 2 (17%)
Chills 0 1 (13%) 1 (14%) 4 (33%)
Myalgias 0 1 (13%) 0 4 (33%)
Lightheadedness 0 2 (25%) 0 1 (8%)
Hypovolemia 0 0 0 0