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Table 1 Proportion of subjects with diarrhea, incubation period, stool output and episode duration among 30 volunteers experimentally infected with ETEC strain TW10598 (STh LT-CS2 CS3 CS21; O6:K15:H16)

From: Experimental infection of healthy volunteers with enterotoxigenic Escherichia coliwild-type strain TW10598 in a hospital ward

Target dose (CFU) No. of volunteers No. with diarrhea Attack risk Median severity Mean incubation period, hours (range) Mean 24 hrs maximum stool output, grams (range) Mean whole episode stool output, grams (range) Mean episode duration, hrs (range) Mean 24 hrs maximum stool output, count (range)
1 × 106 3 2 67% Mild-Moderate 60 (48–72) 416 (330–502) 613 (510–717) 37 (25–48) 2 (2–2)
1 × 107 8 5 63% Moderate 37 (9–70) 676 (407–1352) 877 (407–1842) 38 (6–72) 5 (3–9)
1 × 108 7 6 86% Moderate-Severe 38 (13–78) 965 (318–1790) 1466 (450–3608) 46 (18–78) 6.5 (3–13)
1 × 109 12 10 83% Moderate 30 (10–57) 538 (295–918) 687 (358–1315) 33 (1–106) 4.2 (1–9)