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Table 2 Reproduction numbers from the 1957 influenza A/H2N2 pandemic

From: Estimates of the reproduction number for seasonal, pandemic, and zoonotic influenza: a systematic review of the literature

Location Wavea Study population Mean GT/SIb Reproduction number (R) 95% CIc Basic or effective Case definition Reference Year published
Netherlands 2nd Community 3 1.39   Basic Unconfirmed deaths [38] 2010
United Kingdom 2nd Community 2.6 1.70   Basic Unconfirmed deaths [10] 2006
United Kingdom 2nd Community 3 1.5–1.6   Basic Unconfirmed illness [39] 2008
United Kingdom 2nd Community 4 1.7–1.8   Basic Unconfirmed illness [39] 2008
United Kingdom 2nd Community 4.1 1.50   Effective Unconfirmed illness [25] 2006
United Kingdom 2nd Community NR 1.65   Basic Serology confirmed infection [26] 2005
USA 2nd Community 4 1.70   Basic Unconfirmed illness [40] 2004
Median reproduction number for the 1957 pandemic: 1.65; Interquartile range 1.53–1.70
  1. aThe 1957 influenza A/H2N2 pandemic began in February 1957 in southern China and spread to Singapore and Hong Kong in April [1]. The virus was first isolated in the United States in June 1957 and was associated with a mild first wave of illnesses [1, 41]. The peak of the pandemic occurred during the second wave in the Northern Hemisphere in October 1957 and was followed by a third wave in January 1958.
  2. bThe generation time (GT) or serial interval (SI) assumed in the reproduction number estimation.
  3. cConfidence interval.
  4. NR = Not reported.
  5. This table is also available as a .csv file as Additional file 2.