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Table 5 Frequency of mutations in rrs gene showing nucleotide change in 120 rrs -resistant strains of M. tuberculosis complex

From: Molecular detection and characterization of resistant genes in Mycobacterium tuberculosis complex from DNA isolated from tuberculosis patients in the Eastern Cape province South Africa

 

rrsgene mutation positions

 

S2169,70 → A

R2201 → R

K2202 → E

Deletion2207

No. of strains (%)

120 (100%)

70 (58.3%)

80 (66.7%)

50 (41.7%)

  1. S = Serine; A = Alanine; R = Arginine; K = Lysine; E = Glutamic acid.