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Table 3 Frequency of mutations in katG gene codons 293, 315 and 463 in 140 INH-resistant strains of M. tuberculosis complex

From: Molecular detection and characterization of resistant genes in Mycobacterium tuberculosis complex from DNA isolated from tuberculosis patients in the Eastern Cape province South Africa

 

katGgene mutation positions

 

N293 → G

S293 → G

S315 → T

S315 → N

T315 → N

T315 → S

R 463 → L

No. of strains (%)

10 (7.1%)

10 (7.1%)

20 (14.3%)

50 (35.7%)

10 (7.1%)

10 (7.1%)

10 (7.1%)

  1. N = Asparagine; G = Glycine; S = Serine; T = Threonine; R = Arginine; L = Leucine.