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Table 2 Initial data on the investigated 30 clinical isolates M.tuberculosis observed among 29 tuberculosis patients

From: Characterization of extensively drug-resistant Mycobacterium tuberculosis isolates circulating in Siberia

Region

S

H

Et

E

Cp

A

K

R

Of

Z

Duration of illness

Age ranges

Sex

DS

Comorbidities

Epidemic history

Complaints

6

2

1

1

1

1

1

1

1

1

1

1

2

I

f

FCPT

No

Family

Cough

9

1

1

1

0

0

1

1

1

1

1

1

2

III

m

FCPT

No

Prison

Cough, shortness of breath

15

3

1

1

1

1

1

1

1

1

1

1

2

II

m

FCPT

HCV, drug addiction

Prison

Cough, shortness of breath, fever,

17

2

1

1

1

1

0

0

1

1

1

1

2

I

f

FCPT

Chronic bronchitis

Family

Cough, hemoptysis

20

4

1

1

1

0

0

1

0

1

0

1

2

II

f

IPT

No

Professional (the nurse)

Cough

21

3

1

1

0

1

1

1

1

1

1

1

1

I

m

IPT

Chronic gastritis

No

Weakness, sweating, fever, hemoptysis

37

3

1

1

1

0

0

1

1

1

1

1

2

II

f

IPT

Neurocirculatory dystonia, encephalopathy, cervical osteochondrosis, cervicalgia, cyst of the right lobe of the liver

Professional (the physiacion)

Shortness of breath

38

9

1

1

1

1

0

0

1

1

1

1

2

I

f

DPT

No

Family

Shortness of breath, weakness

48

10

1

1

1

1

1

1

1

1

1

1

2

II

m

DPT

Peptic ulcer, chronic cholecystitis, HCV, HBV

Family/professional (corpsman in the morgue)

Cough

78

3

1

1

1

1

1

0

0

1

1

1

2

II

f

FCPT

HCV

Family

No

87

3

1

1

0

0

0

0

1

1

1

0

1

I

f

FCPT

Bronchitis after postural drainage

Family

Shortness of breath

94

5

1

1

1

1

1

1

1

1

1

1

2

II

f

FCPT

Obstructive bronchitis, bronchial asthma, syphilis

No

Cough, weakness, shortness of breath

96

4

1

1

1

1

1

0

0

1

1

1

2

I

f

FCPT

HCV

Family

Weaknwss, chest pain

128

6

1

1

1

0

1

1

1

1

1

1

2

I

m

FCPT

Duodenal ulcer

No

Cough

133

7

1

1

1

0

0

1

1

1

1

1

2

II

m

FCPT

Chronic pancreatitis

No

Cough

145

3

1

1

0

1

1

1

1

1

1

0

2

II

m

IPT

HCV, drug addiction

Prison (1998–2001)

Cough

158

3

1

1

1

1

1

1

1

1

1

0

1

I

m

IPT

No

No

Cough, shortness of breath, sweating

169

6

1

1

1

1

0

1

1

1

1

1

2

I

f

FCPT

Respiratory failure 1 level, chronic adnexitis

No

Cough, fever, hemoptysis

171

3

1

1

1

1

0

0

0

1

1

1

2

I

m

FCPT

Secondary bronchial obstruction, respiratory failure 2, heart failure, cachexia

No

Cough, shortness of breath, weakness, chest pain, weight loss

235

3

1

1

1

1

1

0

1

1

1

1

1

IV

m

CP

Diabetes, steatohepatitis, chronic cholecystitis, cholelithiasis

No

Cough, shortness of breath, weakness

236

7

1

1

1

1

1

1

1

1

1

1

2

II

m

FCPT

Chronic pancreatitis

No

Cough

238

3

1

1

1

1

1

1

1

1

1

1

2

IV

m

FCPT

Obstructive bronchitis, emphysema, heart failure

No

Shortness of breath

275

8

1

1

1

1

1

1

1

1

1

1

1

I

f

FCPT

HCV, bronchitis

Contact with neighbors

Cough, weakness, shortness of breath

276

3

1

1

1

1

1

1

1

1

1

0

1

IV

m

DPT

Gastrectomy, HCV, respiratory failure, cachexia

No

Cough, weight less

285

8

1

1

1

1

1

1

1

1

1

1

2

II

m

FCPT

HCV

Prison (2007–2009)

No

287

3

1

1

1

1

1

1

1

1

1

1

2

II

m

IPT

HIV, HCV, sinusitis, stomatitis, drug addiction

No

Cough, shortness of breath, weakness, sweating

300

11

1

1

0

0

1

1

1

1

1

0

2

II

m

FCPT

Obstructive bronchitis

Prison

Cough, fever, chest pain

309

3

1

1

1

1

1

0

1

1

1

1

2

II

m

IPT

HIV, HCV, drug addiction

Contact with neighbors

Cough with sputum

1084

8

1

1

1

1

1

1

1

1

1

1

2

I

m

CP

Obstructive bronchitis

Family

Cough, chest pain

4548

3

1

1

1

1

0

1

1

1

1

1

2

IV

f

FCPT

Obstructive bronchitis, hypertonic disease II

Death

Shortness of breath, tiredness

  1. Note: In the column ‘region’ numbers denote: 1 - Jewish Autonomous Oblast, 2 – the Krasnoyarsk Kray, 3 – Novosibirsk region, 4 – Omsk Oblast, 5 – Chita city, 6 - Kemerovo oblast, 7 – Kamchatka, 8 - The Republic of Khakassia, 9 – The Tuva Republic, 10 - Tomsk, 11 - Altay Republic. Resistance to anti-TB drugs: 1 - resistant, 0 - sensitive. Designation column: S - streptomycin, H - isoniazid, Et - ethionamide, E - ethambutol, CAP - capreomycin, A - amikacin, K-kanamycin, R - rifampicin, Of - ofloxacin, Z - pyrazinamide. In the column “ duration of illness”: 1 - primary tuberculosis, 2 - secondary tuberculosis. In the column «DS» - diagnosis: FCPT - Fibrous-cavernous pulmonary tuberculosis, DPT - disseminated pulmonary tuberculosis, IPT - infiltrative pulmonary tuberculosis, CP - cheesy pneumonia. * - the isolates from one patient.