From: Modeling the impact of novel diagnostic tests on pediatric and extrapulmonary tuberculosis
10-year projected tuberculosis outcomes | |||||||||
---|---|---|---|---|---|---|---|---|---|
Incidence per 100,000 | Prevalence per 100,000 | Mortality per 100,000 | |||||||
Adult total | Adult EPTB | Children | Adult total | Adult EPTB | Children | Adult total | Adult EPTB | Children | |
N (% reduction*) | N (% reduction*) | N (% reduction*) | N (% reduction*) | N (% reduction) | N (% reduction*) | N (% reduction*) | N (% reduction*) | N (% reduction*) | |
Existing standard | 89.5 (Ref) | 13.9 (Ref) | 44.8 (Ref) | 114.8 (Ref) | 34.4 (Ref) | 62.8 (Ref) | 22.8 (Ref) | 7.3 (Ref) | 9.4 (Ref) |
Xpert for adult pulmonary TB | 86.0 (4.0%) | 13.4 (3.7%) | 42.6 (5.0%) | 109.3 (4.8%) | 33.2 (3.5%) | 59.8 (4.9%) | 21.8 (4.5%) | 7.1 (3.0%) | 8.9 (4.8%) |
NAAT- Peds | 86.0 (4.0%) | 13.4 (3.7%) | 42.6 (5.0%) | 109.2 (4.9%) | 33.1 (3.9%) | 58.5 (6.9%) | 21.8 (4.5%) | 7.1 (3.3%) | 8.7 (6.8%) |
NAAT- EPTB | 86.0 (4.0%) | 13.4 (3.7%) | 42.6 (5.0%) | 107.8 (6.1%) | 31.7 (7.9%) | 58.0 (7.7%) | 21.4 (5.9%) | 6.7 (7.6%) | 8.7 (7.6%) |
POC NAAT sputum | 79.6 (11.1%) | 12.5 (10.2%) | 38.6 (13.8%) | 99.8 (13.0%) | 31.0 (9.8%) | 54.4 (13.4%) | 20.0 (12.2%) | 6.7 (8.4%) | 8.1 (13.3%) |
POC NAAT non- sputum | 80.2 (10.4%) | 12.6 (9.6%) | 39.0 (13.0%) | 90.5 (21.2%) | 21.1 (38.8%) | 41.0 (34.7%) | 18.0 (21.3%) | 4.5 (38.5%) | 6.1 (34.7%) |