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Figure 2 | BMC Infectious Diseases

Figure 2

From: Modeling the impact of novel diagnostic tests on pediatric and extrapulmonary tuberculosis

Figure 2

Impact of different tests on pulmonary and extrapulmonary TB (A) incidence and (B) mortality in adults and children. Trajectory of (A) overall tuberculosis (TB) incidence and (B) mortality over 10 years without further intervention (maroon line), with introduction of Xpert for adult pulmonary TB (green line; coverage 15%, 30%, 30% among new, previously treated and failure cases) and introduction of POC sputum NAAT (purple line; coverage of 50%, 80%, 100%). In addition, we project the incremental impact of POC-non-sputum NAAT that was optimized for detection of both pulmonary TB and extrapulmonary TB (EPTB) (orange line) using non-invasive samples thus eliminating a delay in diagnosis of EPTB and being deployed at the same level of coverage as POC sputum NAAT.

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