Community-acquired K. pneumoniaebacteremia | |||||
---|---|---|---|---|---|
Variable | Invasive syndrome (%) | ||||
Yes (n = 76) | No (n = 332) | pvalue | Control (%) (n = 76) | pvalue+ | |
Hypermucoviscosity phenotype of K. pneumoniae | 69 (90.8) | 78 (23.5) | < 0.01* | ||
Male | 40 (52.6) | 150 (45.2) | 0.25 | 40 (52.6) | 0.99 |
Age ≥ 60 yrs | 39 (51.3) | 128 (38.6) | 0.05 | 39 (51.3) | 0.99 |
Diabetes mellitus (DM) | 41 (53.9) | 134 (40.4) | 0.04 | 25 (32.9) | 0.01 |
DM with poor glycemic control (HbA1c ≥ 9%) | 32 (42.1) | 75 (22.6) | < 0.01* | 17 (22.4) | 0.02 |
Cardiovascular diseases | 17 (22.4) | 65 (19.6) | 0.69 | 21 (27.6) | 0.57 |
Liver cirrhosis | 5 (6.6) | 45 (13.6) | 0.12 | 10 (13.2) | 0.28 |
Chronic renal failure | 10 (13.2) | 35 (10.5) | 0.54 | 18 (23.7) | 0.14 |
Malignancy | 4 (5.3) | 33 (9.9) | 0.27 | 18 (23.7) | < 0.01 |
Biliary tract diseases | 2 (2.6) | 20 (6.0) | 0.39 | 8 (10.5) | 0.10 |
Absence of underlying diseases | 12 (15.8) | 44 (13.3) | 0.69 | 9 (11.8) | 0.64 |
Therapy in the month prior to the infection | |||||
Proton-pump inhibitors | 8 (10.5) | 24 (7.2) | 0.47 | 15 (19.7) | 0.17 |
Aspirin | 2 (2.6) | 56 (16.9) | < 0.01* | 8 (10.5) | 0.10 |
Antibiotics | 5 (6.6) | 28 (8.4) | 0.76 | 12 (15.8) | 0.12 |