No indication for tissue tropism in urogenital and anorectal Chlamydia trachomatis infections using high-resolution multilocus sequence typing

Table 1 Demographic and sexual risk behavior characteristics of women and men who have sex with men (MSM) with anorectal Chlamydia trachomatis infections

Variable	Total (N = 392)			Women (N = 185)			MSM (N = 207)
	*	n	(%)	*	n	(%)	*	n	(%)	P
Demographics
Age in years (continuous)	383			185			198			<0.001
Median (IQR)		28	(22–39)		23	(20–26)		38	(31–45)
Age in years (categorical)	383			185			198			<0.001
≤15		1	(0.3%)		1	(0.5%)		0	(0.0%)
15-19		25	(6.5%)		25	(13.5%)		0	(0.0%)
20-24		107	(27.9%)		95	(51.4%)		12	(6.1%)
25-29		72	(18.8%)		41	(22.2%)		31	(15.7%)
30-39		84	(21.9%)		15	(8.1%)		69	(34.8%)
≥40		94	(24.5%)		8	(4.3%)		86	(43.4%)
Sexual behavior
Number of partners in preceding 6 months (continuous)	286			185			188			<0.001
Median (IQR)		4	(2–10)		3	(1–5)		10	(4–20)
Receptive anal intercourse	381			183			198			<0.001
None^a		31	(8.1%)		22	(12.0%)		1	(0.5%)
Safe		70	(18.4%)		16	(8.7%)		54	(27.3%)
Unsafe^b		280	(73.5%)		145	(79.2%)		143	(72.2%)
Notified of STI by a sexual partner	383			185			198			0.961
No		306	(79.9%)		148	(80.0%)		158	(79.8%)
Yes		77	(20.1%)		37	(20.0%)		40	(20.2%)
STI related symptoms	383			185			198			<0.001
No		233	(60.8%)		132	(71.4%)		101	(51.0%)
Yes		150	(39.2%)		53	(28.6%)		97	(49.0%)
HIV status	392			185			207			<0.001
Unknown		19	(4.8%)		3	(1.6%)		16	(7.7%)
Negative		278	(70.9%)		182	(98.4%)		96	(46.4%)
Positive		95	(24.2%)		0	(0.0%)		95	(45.9%)
Received money for sex in preceding 6 months	383			185			198			<0.001
No		354	(92.4%)		158	(85.4%)		196	(99.0%)
Yes		29	(7.6%)		27	(14.6%)		2	(1.0%)

Abbreviations: MSM men who have sex with men, STI sexual transmitted infection, HIV human immunodeficiency virus, IQR interquartile range, P P-value.
Significant P-values in bold.
*Number of individuals with available data.
^aOf all women reporting no receptive anal intercourse, 14 were prostitutes and were also tested for rectal C. trachomatis infections following routine guidelines, 5 women were accidently tested, 3 women were tested for reporting anal discharge, and 1 women was tested due to notification by a sexual partner.
^bEight women reported receptive anal intercourse but condom use was unknown. These were all included as having unsafe receptive anal intercourse, as this would be the most likely explanation for infection.

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