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Table 3 Comparison of M. tuberculosis clustering based on MIRU-12 and MIRU-24 typing

From: Temporal dynamics of Mycobacterium tuberculosis genotypes in New South Wales, Australia

Characteristic Dominant strain families Total
Beijing EAI** Delhi/CAS (N = 1128)
(N = 309) (N = 324) (N = 158)
MIRU number of loci* 12 24 12 24 12 24 12 24
Number of clusters 32 42 35 18 17 5 139 82
Number of clustered isolates# 249 125 190 44 69 12 695 227
% clustering 80.6 40.5 58.6 13.6 43.7 7.6 61.6 20.1
Average cluster size 8 3 5.4 2.4 4.1 2.8 5 2.8
Transmission rate (%)## 70.2 26.9 47.8 8.0 32.9 4.4 49.3 12.8
  1. *MIRU - mycobacterial interspersed repetitive unit.
  2. **EAI – East African Indian strain family (Lineage 3).
  3. #Two or more strains with identical MIRU profiles were considered a cluster.
  4. ##Calculated as (number of clustered isolates - number of clusters)/total number of isolates.