Temporal dynamics of Mycobacterium tuberculosis genotypes in New South Wales, Australia

BMC Infectious Diseases

Table 3 Comparison of M. tuberculosis clustering based on MIRU-12 and MIRU-24 typing

Characteristic	Dominant strain families						Total
	Beijing		EAI**		Delhi/CAS		(N = 1128)
	(N = 309)		(N = 324)		(N = 158)		(N = 1128)
MIRU number of loci*	12	24	12	24	12	24	12	24
Number of clusters	32	42	35	18	17	5	139	82
Number of clustered isolates^#	249	125	190	44	69	12	695	227
% clustering	80.6	40.5	58.6	13.6	43.7	7.6	61.6	20.1
Average cluster size	8	3	5.4	2.4	4.1	2.8	5	2.8
Transmission rate (%)^##	70.2	26.9	47.8	8.0	32.9	4.4	49.3	12.8

*MIRU - mycobacterial interspersed repetitive unit.
**EAI – East African Indian strain family (Lineage 3).
^#Two or more strains with identical MIRU profiles were considered a cluster.
^##Calculated as (number of clustered isolates - number of clusters)/total number of isolates.

ISSN: 1471-2334