|
KIR – HLA Class I
|
Per se
|
LL
|
Borderline
|
TT
|
Controls
|
|---|
|
N = 408
|
N = 21
|
N = 302
|
N = 60
|
N = 413
|
|---|
|
n (%)
|
n (%)
|
n (%)
|
n (%)
|
n (%)
|
|---|
|
KIR2DL1 – C2
|
173 (42.4)
|
10 (47.6)
|
121 (40.0)
|
29 (48.3)
|
188 (45.5)
|
|
KIR2DL1 – C2/C2
|
82 (20.0)
|
5 (23.8)
|
59 (19.5)
|
14 (23.3)
|
79 (19.1)
|
|
KIR2DL2 – C1
|
145 (35.5)
|
8 (38.0)
|
95 (31.4)
|
27 (45.0)
|
134 (32.4)
|
|
KIR2DL2 – C1/C1
|
71 (17.4)
|
2 (9.52)
|
56 (18.5)
|
11 (18.3)
|
95 (23.0)
|
|
KIR2DL3 – C1
|
174 (42.6)
|
9 (42.8)
|
128 (42.3)
|
26 (43.3)
|
184 (44.5)
|
|
KIR2DL3 – C1/C1
|
92 (22.5)
|
3 (14.2)
|
71 (23.5)
|
13 (21.6)
|
116 (28.0)
|
|
KIR3DL1 – Bw4
|
153 (37.5)
|
7 (33.3)
|
118 (39.0)
|
18 (30.0)
|
164 (39.7)
|
|
KIR3DL1 – Bw4/Bw4
|
44 (10.7)
|
2 (9.52)
|
33 (10.9)
|
7 (11.6)
|
54 (13.0)
|
|
KIR3DL2 – A*03/*11
|
99 (24.2)
|
4 (19.0)
|
74 (24.5)
|
15 (25.0)
|
86 (20.8)
|
|
KIR2DS1 – C2
|
70 (17.1)
|
2 (9.52)
|
48 (15.8)
|
14 (23.3)
|
74 (17.9)
|
|
KIR2DS1 – C2/C2
|
38 (9.31)
|
2 (9.52)
|
27 (8.94)
|
7 (11.6)
|
25 (6.05)
|
|
KIR2DS2 – C1
|
111 (27.2)a
|
5 (23.8)
|
74 (24.5)
|
20 (33.3)a
|
85 (20.5)a
|
|
KIR2DS2 – C1/C1
|
51 (12.5)
|
3 (14.2)
|
39 (12.9)
|
6 (10.0)
|
60 (14.5)
|
|
KIR3DS1 – Bw4
|
57 (13.9)
|
1 (4.76)
|
46 (15.2)
|
7 (11.6)
|
59 (14.2)
|
|
KIR3DS1 – Bw4/Bw4
|
21 (5.14)
|
1 (4.76)
|
16 (5.29)
|
4 (6.66)
|
23 (5.56)
|
|
KIR2DL2/2DL2 – C1
|
22 (5.39)b
|
3 (14.2)b
|
10 (3.31)b
|
5 (8.33)b
|
9 (2.17)b
|
|
KIR2DL2/2DL2 – C1/C1
|
14 (3.43)
|
0 (0.0)
|
11 (3.64)
|
2 (3.33)
|
10 (2.42)
|
|
KIR2DL2/2DL3 – C1
|
122 (29.9)
|
6 (28.5)
|
88 (29.1)
|
19 (31.6)
|
124 (30.0)
|
|
KIR2DL2/2DL3 – C1/C1
|
56 (13.7)c
|
2 (9.52)
|
43 (14.2)
|
11 (18.3)
|
82 (19.8)c
|
|
KIR2DL3/2DL3 – C1
|
55 (13.4)
|
4 (19.0)
|
44 (14.5)
|
5 (8.33)
|
62 (15.0)
|
|
KIR2DL3/2DL3 – C1/C1
|
34 (8.33)
|
1 (4.76)
|
25 (8.27)
|
4 (6.66)
|
32 (7.74)
|
-
NOTA: Data represent the number of KIR genes and their respective ligands HLA Class I; the values in parentheses correspond to the percentages of each pair KIR-HLA.
- TT: Tuberculoid, Borderline (BL, BB, BT), LL: Lepromatous.
-
a
KIR2DS2 – C1: P = 0.031, OR = 1.4 (1.0 – 2.0) to per se vs. controls; P = 0.045, OR = 1.9 (1.1 – 3.5) to TT vs. controls.
-
b
KIR2DL2/2DL2 – C1: P = 0.024, OR = 2.6 (1.2 – 5.6) to per se vs. controls; P = 0.045, OR = 4.1 (1.3 – 12.6) to TT vs. controls; P = 0.032, OR = 7.5 (1.9 – 30.1) to LL vs. controls; P = 0.057 (tendency) to Borderline vs. LL.
-
c
KIR2DL2/2DL3 – C1/C1: P = 0.023, OR = 0.6 (0.4 – 0.9) to per se vs. controls.
