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Table 1 Demographic data and clinical characteristics of the patients with emphysematous pyelonephritis

From: Predictors of failure of conservative treatment among patients with emphysematous pyelonephritis

Variable, n (%)

Surviving (n = 39)

Died (n = 5)

P-value

OR

P-value

Median age (y)

60

65

0.32

1. (0.9-1.1)

0.40

Female sex

27 (69.2)

5 (100)

0.30

-

-

Underlying condition

     

Diabetes mellitus

27 (69.2)

3 (60)

0.65

0.7 (0.1-4.5)

0.68

Hypertension

14 (35.9)

3 (60)

0.36

2.7 (0.4-18)

0.31

Prior cerebrovascular accident

4 (10.3)

1 (20)

0.47

2.2 (0.2-24.7)

0.53

Down syndrome

1 (2.6)

0 (0)

1.00

-

-

Liver cirrhosis

3 (7.7)

1 (20)

0.39

3 (0.3-36.1)

0.39

Obstructive uropathy

19 (48.7)

4 (80)

0.35

4.2 (0.4-41.1)

0.22

Urolithasis

19 (48.7)

3 (60)

1.00

1.6 (0.2-10.5)

0.64

Laboratory finding

     

Leukocyte (103/μL)

13.8

15.40

0.77

1.0 (0.9-1.1)

0.83

Platelet count (103/mL)

195.0

106.0

0.08

0.9 (0.8-1.0)

0.15

Thrombocytopenia

8 (20.5)

3 (60)

0.09

5.8 (0.8-40.9)

0.08

(≤120,000/mL)

Albumin (g/dL)

2.7

2.8

0.43

0.4 (0.1-2.5)

0.36

Hypoalbuminemia

17 (47.2)

5 (100)

0.05

-

-

(<3.0 g/dL)

Hyponatremia

10 (25.6)

2 (40)

0.60

1.9 (0.3-13.3)

0.50

C-reactive Protein (mg/dL)

9.2

5.98

0.67

1.0 (0.9-1.1)

0.68

Pyuria

32 (88.9)

5 (100)

1.00

-

-

Hematuria

21 (58.3)

5 (100)

0.14

-

-

HbA1C >8%

17 (47.2)

2 (40)

1.00

0.7 (0.1-5.6)

0.73

Image study

     

Radiologic classification

21 (56.8)

1 (20)

0.17

0.2 (0.02-2.3)

0.22

(3A,3B,4)a

Involved site (left)

23 (59.0)

3 (60)

1.00

0.9 (0.1-6.3)

0.95

Bilateral involvement

2 (5.1)

0 (0)

1.00

-

-

Need for hemodialysis

2 (5.1)

3 (60)

0.01

27.8 (2.8-272.9)

0.004

Inappropriate empirical antibiotic use

3 (8.6)

3 (60)

0.02

16.0 (1.9-136.7)

0.01

Bacteremia

16 (41.0)

4 (80)

0.16

5.8 (0.6-56.4)

0.13

Shock

5 (12.8)

4 (80)

0.004

27.2 (2.5-295.0)

0.01

Acute kidney injury

18 (46.2)

4 (80)

0.35

4.7 (0.5-45.6)

0.19

Altered mental status

11 (28.2)

4 (80)

0.04

10.2 (1.0-101.5)

0.05

Polymicrobial infection

7 (18.0)

5 (100)

0.001

-

-

  1. aRadiologic classification is based on the extent of air seen on computed tomography (CT): class 3A, extension of gas or abscess to the perinephric space; class 3B, extension of gas or abscess to the pararenal space; class 4, bilateral EPN or a solitary kidney with EPN.