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Table 4 Predictive factors of complicated diseases in patients with EV71 infection

From: The correlation between the presence of viremia and clinical severity in patients with enterovirus 71 infection: a multi-center cohort study

  Uncomplicated EV71 infection (Grade 1) (n = 88) Complicated EV71 infection (Grade 2 to 4) (n = 136) pvaluea
Age (median with range, years) 3.08 (0–15) 2.60 (0–14) 0.06
Gender    
 Male 56 (64%) 84 (62%) 0.89
 Female 32 (36%) 52 (38%)  
Fever b 72 (82%) 132 (97%) <0.001
Fever > 3 days 34 (39%) 83 (61%) 0.002
Skin rash 86 (97%) 124 (94%) 0.21
Oral ulcer 85 (97%) 132 (97%) 1.00
Viremia    
 Yes 23 (26%) 36 (26%) 0.96
 No 65 (74%) 100 (74%)  
Viral load (median with range, log10 copies/mL) 3.34 (0.88 - 6.99) 3.50 (1.29 - 6.51) 0.80
  1. Values expressed as n(%), unless otherwise indicated.
  2. aThe chi-square and Fisher’s exact test was used for categorical variables, and the Mann–Whitney test was used for comparison of the viral load.
  3. bFever was defined as any body temperature over 38 degrees Celsius.