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Table 1 Age, gender and clinical severity of patients with EV71 infection

From: The correlation between the presence of viremia and clinical severity in patients with enterovirus 71 infection: a multi-center cohort study

 

Case number (n = 224)

Percentage

Age (median with range, years)

2.71 (0–15)

 

  ≤ 3 y/o

102

46%

  > 3 y/o

122

54%

Gender

  

  Male

140

63%

  Female

84

38%

Clinical Severity (Grade 1 to 4)

  

  Uncomplicated diseasea

88

39%

  Myoclonic jerk or aseptic meningitis

101

45%

  Severe CNS involvementb without cardiopulmonary failure

22

10%

  Severe CNS involvementb with cardiopulmonary failure

13

6%

Outcomes

  

  Complete recovery

219

98%

  With sequelaec

3

1%

  Death

2

1%

  1. aUncomplicated cases includes uncomplicated HFMD, herpangina or febrile illness.
  2. bSevere CNS involvement includes encephalitis, encephalomyelitis or polio-like syndrome.
  3. cAmong the three patients with sequelae, one patient had cervical mye1itis and thoracic spine arachnoiditis and had flaccid paralysis of right arm, another had rhombencephalitis complicated with left arm paralysis and ventilator-dependence after dishcharge, the other had paralysis of left arm and lower limbs and also needed non-invasive positive pressure ventilation after discharge.