Table 3 Inpatient and one-year TB rates and mortality of patients admitted to the medical wards of a tertiary, referral hospital in Sub-Saharan Africa
Sub-population* | No. patients | No. of days admitted | No. of days in cohorting | No. of days with an index case in the same bay | No. of days adjacent to index case | Average TB exposure index (SD) | Overall inpatient mortality (%) | TB incidence per 100 persons per year of follow up | Overall Mortality per year of follow-up (%) | TB-related mortality per year of follow up (%) |
|---|---|---|---|---|---|---|---|---|---|---|
Place of admission | ||||||||||
General bay only | 883 | 5475 | NA | 1035 | 475 | 6.6 (5.9) | 168 (19.0) | 16 | 17 | 10 |
General bay AND cohorting bay | 80 | 936 | 504 | 1113 | 432 | 18.8 (8.6) | 2 (2.5) | 10 | 9 | 6 |
Cohorting bay only | 131 | 2319 | 1349 | 3211 | 1576 | 33.2 (16.1) | 8 (6.1) | 15 | 31 | 6 |
HIV status | ||||||||||
Positive | 690 | 5728 | 1795 | 3894 | 1787 | 12. (14.1) | 118 (17.1) | 37 | 43 | 21 |
Negative | 404 | 3001 | 58 | 1465 | 696 | 8.0 (6.3) | 60 (14.9) | 4 | 14 | 1 |
CD4 cell count | ||||||||||
< 50 cells/mL | 58 | 435 | 198 | 598 | 205 | 11.2 (11.5) | 4 (6.9) | 2 | 2 | 4 |
50 – 99 cells/mL | 100 | 880 | 272 | 625 | 283 | 12.8 (14.0) | 14 (14) | 6 | 3 | 4 |
100 - 199 cells/mL | 170 | 1343 | 448 | 613 | 434 | 12.0 (13.7) | 26 (15.3) | 6 | 4 | 10 |
200 – 349 cells/mL | 203 | 1786 | 440 | 759 | 393 | 11.1 (12.8) | 35 (17.3) | 9 | 5 | 9 |
350 – 499 cells/mL | 73 | 664 | 183 | 672 | 209 | 13.2 (15.1) | 15 (20.5) | 7 | 5 | 9 |
>500 cells/mL | 86 | 619 | 255 | 627 | 263 | 8.0 (6.3) | 24 (28.0) | 7 | 2 | 7 |
Diagnosis of PTB during admission | ||||||||||
PTB | 215 | 3139 | 1803 | 2876 | 1978 | 27.1 (15.8) | 11 (5.1) | 28 | 17 | 26 |
No TB | 979 | 5590 | 50 | 2483 | 505 | 6.6 (5.9) | 167 (17.1) | 13 | 5 | 31 |