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Table 2 HZ pain severity/interference (ZBPI) and HRQOL impact (SF-36 & EQ-5D) at initial visit: ZQOL study subgroup analyses

From: Burden of herpes zoster in the UK: findings from the zoster quality of life (ZQOL) study

Outcome variable

Age

Gender

Antiviral

Pain Severity

 

Spearman’s rho

P

Male (n = 105)

Female (n = 122)

P

<72 hours (n = 159)

≥ 72 hours (n = 43)

p

No pain (n = 23)

Mild (n = 66)

Moderate (n = 48)

Severe (n = 79)

p

Zoster Brief Pain Inventory (ZBPI)

             

Pain Severity

−0.0720

NS

3.4

4.0

*

3.9

3.4

NS

N/A

N/A

N/A

N/A

N/A

Pain Interference

−0.0173

NS

3.1

3.4

NS

3.5

2.6

*

0.7

1.7

3.5

5.3

*** †

Short-Form Health Survey 36 (SF-36)

             

SF-36 Physical Component Summary (PCS)

−0.0903

NS

40.9

42.1

NS

43.2

46.2

NS

48.3

44.8

41.0

36.07

***

SF-36 Mental Component Summary (MCS)

0.0840

NS

45.9

39.9

*** †

41.5

46.9

NS

46.4

45.5

38.5

41.1

**

EuroQoL 5-Dimensions (EQ-5D)

             

EQ-5D Self-Rated Health (SRH)

−0.0295

NS

66.7

59.6

**

63.8

73.1

NS

70.0

70.1

59.7

54.6

***

EQ-5D Health State Index (HSI)

−0.0635

NS

0.68

0.61

NS

0.63

0.70

NS

0.81

0.70

0.66

0.52

***

  1. NS p ≥ 0.05, *p < 0.05; **p < 0.01; ***p <0.001. † = clinically meaningful difference.