Results of two-way sensitivity analyses varying the vaccination coverage and the maximum vaccination age. These charts show how many additional symptomatic influenza cases are prevented in scenario 2 during the 10-year evaluation period in Germany when compared to scenario 1. In scenario 1, TIV is used for all age classes with constant age-specific vaccination coverage, as reported for Germany. Scenario 1 remains unchanged in all analyses presented by these graphs. Scenario 2 assumes that annual vaccination of children up to a given maximum age (see numbers on the right hand side) is recommended in Germany, starting in 2012. In scenario 2, the vaccination coverage of children from 2 years up to the recommended age is increased in three annual steps, starting from the baseline value and finally reaching the coverage given on the horizontal axis; the vaccination coverage of children in other age groups and of adults is kept at the baseline value (which is also used in scenario 1). (a) TIV is used for all children and adults in scenario 2; (b) LAIV is used for all children from 2 years up to the recommended maximum age of childhood vaccination, and TIV is used for all others; (c) LAIV is used for all children from 2 years up to the recommended maximum age of childhood vaccination (with increasing coverage) and for all older children up to 17 years (with constant coverage); TIV is used for all others.