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Table 4 Determinants of clearance for the most prevalent HR-HPV types

From: Persistence, clearance and reinfection regarding six high risk human papillomavirus types in Colombian women: a follow-up study

Time independent variables

HPV-16

HPV-18

HPV-45

HPV-58

  

Multivariable model HR (95% CI)

Multivariable model HR (95% CI)

Multivariable model Tm R (95% CI)

Multivariable model Tm R (95% CI)

Age

>50

0.99 (0.53-1.86)

0.59 (0.18-1.87)

1.13 (0.63-2.02)

0.94 (0.63-1.38)

 

35-50

1.14 (0.66-1.96)

0.79 (0.35-1.75)

0.77 (0.49-1.20)

1.26 (0.89-1.79)

 

<35

Reference

Reference

Reference

Reference

City

Other city

2.58 (1.51-4.4)

1.21 (0.51-2.9)

0.97 (0.62-1.52)

1.79 (1.33-2.39)

 

Bogota

Reference

Reference

Reference

Reference

Ethnicity

Afrodescendant

2.35 (0.69-7.93)

0.85 (0.11-6.61)

0.42 (0.16-1.12)

-

 

Mestizo

Reference

Reference

Reference

Reference

 

Other*

-

-

-

1.17 (0.47-2.89)

Contraceptive method

No method

1.01 (0.65-1.59)

0.75 (0.33-1.73)

0.84 (0.56-1.27)

0.98 (0.73-1.30)

 

Hormonal

1.45 (0.72-2.96)

1 (0.35 -2.9)

0.76 (0.45-1.26)

0.97 (0.54-1.72)

 

Other

Reference

Reference

Reference

Reference

Lifetime sexual partners

1

1.24 (0.83-1.86)

1.2 (0.61-2.51)

1.05 (0.72-1.52)

1.10 (0.84-1.44)

 

>1

Reference

Reference

Reference

Reference

Age at first Intercourse

≥18

0.93 (0.6-1.41)

1.08 (0.53-2.19)

1.23 (0.85-1.77)

1.13 (0.85-1.51)

 

<18

Reference

Reference

Reference

Reference

Coinfection

Yes

0.87 (0.46-1.65)

2.49 (0.54-11.45)

1.06 (0.46-2.45)

0.87 (0.58-1.32)

 

No

Reference

Reference

Reference

Reference

Viral Load**

Low

2.1 (0.87-5.15)

0.48 (0.08-2.93)

1.27 (0.76-2.12)

1.36 (0.81-2.29)

 

Middle

1.49 (0.64-3.51)

0.74 (0.24-2.27)

1.61 (1.01-2.57)

1.04 (0.61-1.78)

 

High

Reference

Reference

Reference

Reference

  1. *Since only 2 women of other ethnicity had HPV-58 (1 Afrodescendant and 1 Indigenous) they were put in a category “Other”, just for this type.
  2. **Low viral load meant a viral load below 9.99E + 5, middle 1.00E + 6 to 9.99E + 9 and high meant a viral load higher than 1.00E + 10.
  3. Values in bold = p < 0.05.
  4. HPV Human papillomavirus, CI Confidence interval, HR Hazard ratio, Tm R Time ratio.