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Table 1 Pearson correlation matrixes showing Pearson correlation coefficients (r) of resistance between pairs of antibiotics for a) E. coli , b) K. pneumonia , c) K. oxytoca , d) E. cloacae , e) P. aeruginosa

From: Antimicrobial co-resistance patterns of gram-negative bacilli isolated from bloodstream infections: a longitudinal epidemiological study from 2002–2011

a) Pearson correlation matrix (r) for E. coli
  Cefazolin Ceftriaxone Ciprofloxacin TMP-SMX Pip-tazo Tic-clav
Cefazolin (n = 1783)       
Ceftriaxone (n = 1783) 0.808      
Ciprofloxacin (n = 1783) 0.487 0.290     
TMP-SMX (n = 1783) 0.770 0.503 0.871    
Pip-tazo (n = 846) 0.702 0.623 0.973 0.865   
Tic-clav (n = 1063) 0.885 0.299 0.733 0.839 nd  
b) Pearson correlation matrix (r) for K. pneumoniae
  Cefazolin Ceftriaxone Ciprofloxacin TMP-SMX Pip-tazo Tic-clav
Cefazolin (n = 480)       
Ceftriaxone (n = 480) 0.935      
Ciprofloxacin (n = 480) 0.630 0.566     
TMP-SMX (n = 480) 0.719 0.689 0.274    
Pip-tazo (n = 163) 0.917 0.982 0.886 0.778   
Tic-clav (n = 295) 0.893 0.677 0.648 0.635 nd  
c) Pearson correlation matrix (r) for K. oxytoca
  Cefazolin Ceftriaxone Ciprofloxacin TMP-SMX Pip-tazo Tic-clav
Cefazolin (n = 127)       
Ceftriaxone (n = 127) 0.576      
Ciprofloxacin (n = 127) 0.619 0.952     
TMP-SMX (n = 127) 0.598 −0.005 −0.184    
Pip-tazo (n = 71) 0.011 −0.222 −0.349 −0.174   
Tic-clav (n = 65) 0.649 0.773 0.773 0.013 nd  
d) Pearson correlation matrix (r) for E. cloacae
  Ceftriaxone Ciprofloxacin TMP-SMX Pip-tazo Tic-clav  
Ceftriaxone (n = 170)       
Ciprofloxacin (n = 170) 0.688      
TMP-SMX (n = 170) 0.611 0.172     
Pip-tazo (n = 83) 0.927 0.542 0.781    
Tic-clav (n = 96) 0.944 0.613 0.781 nd   
e) Pearson correlation matrix (r) for P. aeruginosa
  Ceftazidime Ciprofloxacin Pip-tazo Tic-clav   
Ceftazidime (n = 115)       
Ciprofloxacin (n = 115) −0.457      
Pip-tazo (n = 60) 0.177 0.225     
Tic-clav (n = 65) 0.888 −0.100 nd    
  1. Number of isolates (n) included in each matrix is listed for each row. Pearson coefficients (r) which are bolded represent pairs with p values ≤ 0.05, while those that are bolded and italicized trended towards significance with p values > 0.05 ≤ 0.07. Note: TMP-SMX is trimethoprim-sulfamethoxazole, Pip-tazo is piperacillin-tazobactam, Tic-clav is ticarcillin-clavulanate; nd is not determined as isolates did not consistently have both Pip-tazo and Tic-clav susceptibilities reported.