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Table 3 Characteristics of pyrosequencing of pretreatment serum samples from 25 HCV-positive patients receiving PEG-IFN α and ribavirin treatment

From: Deep sequencing of hepatitis C virus hypervariable region 1 reveals no correlation between genetic heterogeneity and antiviral treatment outcome

Number of sequenced reads aligned to reference genome

72 070

Number of sequenced nucleotides

15 100 000

Median of reads per patient (IQR)

2540 (2488)

Mean number of haplotypes per patient after ShoRAH

30.6

• Responders

38.4

• Non-responders

23.4

Most abundant haplotype

57.09%

Least abundant haplotype

0.1%