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Table 3 Characteristics of pyrosequencing of pretreatment serum samples from 25 HCV-positive patients receiving PEG-IFN α and ribavirin treatment

From: Deep sequencing of hepatitis C virus hypervariable region 1 reveals no correlation between genetic heterogeneity and antiviral treatment outcome

Number of sequenced reads aligned to reference genome 72 070
Number of sequenced nucleotides 15 100 000
Median of reads per patient (IQR) 2540 (2488)
Mean number of haplotypes per patient after ShoRAH 30.6
• Responders 38.4
• Non-responders 23.4
Most abundant haplotype 57.09%
Least abundant haplotype 0.1%