Table 1 Main characteristics of 45 kidney or liver transplant patients with TB

Age, mean years ± SD

37.9 ± 10.0

Gender, number of male/number of female

34/11

Temperature of 39°C or greater

15 (33.3)

Primary kidney or liver disease, n (%)

 Glomerulonephritis

33 (73.3)

 Diabetes

7 (15.6)

 Adult polycystic disease

1 (2.2)

 Liver cirrhosis

2 (4.4)

 Other

2 (4.4)

Donor type, n (%)

 Cadaveric

32 (71.1)

 Living

12 (26.7)

 DCD

1 (2.2)

The type of transplantation, n (%)

 Liver

2 (4.4)

 Kidney

43(95.6)

 Two or more transplants

4 (8.9)

Immunosuppressive drugs, n (%)

 Methylprednisolone

45 (100)

 Prednisone

45 (100)

 Mycophenolate mofetil

44 (97.8)

 Tacrolimus

34 (75.6)

 Cyclosporine

10 (22.2)

 Sirolimus

1 (2.2)

 Antilymphocytic or antithymocytic agents

7 (15.6)

Time of TB diagnosis posttransplant, no. of cases (%)

 < 7 mo

13 (28.9)

 7th to 12th mo

4 (8.9)

 > 12 mo

28 (62.2)

Evidence of latent TB (No. of positive test/No. of patients tested)

17 (37.8)

 Untreated TB lesion in chest plain radiograph

10/40 (25.0)

 Preop PPD test positive

10/36 (27.8)

 Preop IGRA test positive

1/4 (25.0)

 Recent TB contact history

1/45 (2.2)

Type of TB, n (%)

 Pulmonary

28 (62.2)

 Extrapulmonary¹

4 (8.9)

 Disseminated

13 (28.9)

Diagnostic modalities (No. of positive test/No.of patients tested)

 Culture positive

23/38 (60.5)

 Smear positive

15/36 (41.7)

 PCR positive

12/20 (60.0)

 Pathology only

3/3 (100.0)

 IGRA positive

6/30 (20.0)

 PPD positive

5/20 (25.0)

Diabetes mellitus, n (%)

7 (15.6)

Rejection within 6 months prior to TB, n (%)

15 (33.3)

CMV infection within 3 months prior to TB

18 (40)

HCV, HBV

10 (22.2)

Major infection within 3 months prior to TB

13 (28.9)

ESR at the onset of TB > 40 mm/h

18 (40.0)

Creatinine at the onset of TB > 2 mg/dl

10 (22.2)

Crude mortality

4 (8.9)